Aspirin . By Sauligno - Own work, CC BY-SA 3.0, link

Israeli Study: Aspirin Helps Protect against Covid-19

Guest essay by Eric Worrall

Do not take aspirin without consulting your doctor – aspirin use, even in small doses, can have nasty and sometimes fatal side effects. But a recent Israeli study of 10,477 patient records suggests a 29% reduction in Covid-19 infection and fatalities amongst regular users of therapeutic aspirin.

Aspirin may protect against COVID-19, Israeli research finds

People who take small doses are 29% less likely than others to test positive, researchers say; those who do get COVID recover faster, and with reduced aftereffects

By NATHAN JEFFAY Today, 3:20 pm 

Aspirin, one of the oldest and most widely used drugs, is preventing COVID-19 infections, Israeli scientists have claimed in “exciting” findings.

In the peer-reviewed research, they found that in a sample of Israeli PCR tests, patients who take small doses of aspirin were 29 percent less likely to test positive. They cross-referenced 10,477 results with medical records covering what preventive drugs patients take.

“We were really excited to see a big reduction in the proportion of people testing positive, and this gives a promising indication that aspirin, such a well-known and inexpensive drug, may be helpful in fighting the pandemic,” Milana Frenkel-Morgenstern of Bar-Ilan University told The Times of Israel.

The aspirin study focused on people who take “baby” 75 milligram doses of the drug for primary prevention of cardiovascular diseases, but don’t already have such diseases. Results were adjusted to account for age and co-morbidities.

“The fact we saw that it’s not just the likelihood of infection but also disease duration points to the possibility of benefits, in biological terms, of taking aspirin,” he said.

Read more: https://www.timesofisrael.com/aspirin-may-protect-against-covid-19-israeli-research-finds/

The abstract of the study;

The use of aspirin for primary prevention of cardiovascular disease is associated with a lower likelihood of COVID-19 infection

Eugene Merzon 1 2Ilan Green 1 2Shlomo Vinker 1 2Avivit Golan-Cohen 1 2Alessandro Gorohovski 3Eva Avramovich 1 3Milana Frenkel-Morgenstern 4Eli Magen 1 5

PMID: 33621437
DOI: 10.1111/febs.15784
Abstract

Acetylsalicylic acid (aspirin) is commonly used for primary and secondary prevention of cardiovascular diseases. Aspirin use is associated with better outcomes among COVID-19 positive patients. We hypothesized that aspirin use for primary cardiovascular disease prevention might have a protective effect on COVID-19 susceptibility and disease duration. We conducted a retrospective population-based cross-sectional study, utilizing data from the Leumit Health Services database. The proportion of patients treated with aspirin was significantly lower among the COVID-19-positive group, as compared to the COVID-19-negative group (73 (11.03 %) vs. 1548 (15.77%); p=0.001). Aspirin use was associated with lower likelihood of COVID-19 infection, as compared to non-users (adjusted OR 0.71 (95% CI, 0.52 to 0.99; p=0.041). Aspirin users were older (68.06 ± 12.79 vs. 56.63 ± 12.28 years of age; p<0.001), presented a lower BMI (28.77±5.4 vs. 30.37±4.55; p<0.0189) and showed higher prevalence of hypertension (56, 76.71%), diabetes (47, 64.38%) and COPD (11, 15.07%) than showed the aspirin non-users (151, 25.64%, p<0.001; 130, 22.07%, p<0.001; and 43, 7.3%, p=0.023, respectively). Moreover, COVID-19 disease duration (considered as the time between the first positive and second negative COVID-19 RT-PCR test results) among aspirin users was significantly shorter, as compared to aspirin non-users (19.8±7.8 vs. 21.9± 7.9 p= 0.045). Among hospitalized COVID-positive patients, a higher proportion of surviving subjects were treated with aspirin (20, 19.05%), as opposed to 1 dead subject (14.29%), although this difference was not significant (p=0.449). In conclusion, we observed inverse association between the likelihood of COVID-19 infection, disease duration and mortality and aspirin use for primary prevention.

Read more: https://pubmed.ncbi.nlm.nih.gov/33621437/

The study appears to focus on the apparent correlation, they don’t appear to delve into the reason for the apparent therapeutic benefit.

One possible explanation, Aspirin is an anti-inflammatory, which might be the reason for its apparent effectiveness.

This isn’t the first time I’ve seen claims about the efficacy of an anti-inflammatory against Covid. Another powerful anti-inflammatory, Butesonide, was recently claimed by Oxford University and Queensland University to reduce severe Covid symptoms by 90% and dramatically improve survival.

The much maligned Hydroxychloroquine, once a widely used an anti-malarial, has a secondary use as a long term anti-inflammatory treatment for arthritis. My French friend told me hydroxychloroquine was a non-prescription over the counter medication in France, until President Macron banned it in early 2020, to stop people self medicating to treat their Covid symptoms.

I don’t know about you guys, but I think I’m starting to see a pattern. Surely this coincidence of independent claims that three unrelated powerful anti-inflammatory drugs are therapeutically effective against Covid-19 is worth someone in the medical community taking a closer look.

A note of caution – these are early days. It is possible that claims of Covid therapeutic benefit for any or all of the drugs I listed are wrong.

But it is also possible claims of Covid therapeutic benefit for all three drugs I mentioned are true. If the three listed anti-inflammatory medications help reduce Covid symptoms, because of their anti-inflammatory properties, these three anti-inflammatories could just the tip of the iceberg – there could be a whole range of anti-inflammatories which are useful for treating Covid. Perhaps somewhere out there is a cheap, generic anti-inflammatory which is even more effective than the claimed effectiveness of Butesonide, just sitting on a shelf somewhere waiting for some doctor to notice it.

Update (EW): A few commenters are dissing my warning about the health risks of Aspirin, but please accept there are genuine serious risks. Some people have health conditions like poor renal function, which even low dose aspirin can worsen. Or people already taking blood thinners like Warfarin are taking a huge risk if they take aspirin in addition to their other medications, without consulting with their doctor first. Aspirin may also increase the risk of developing nasty conditions like Crohns Disease. Asthmatics should be very careful with Aspirin, with around 20% of asthmatics aspirin makes their asthma symptoms worse. I’m sure there are plenty of other ways Aspirin can mess you up. Like I said, please talk to your doctor before self medicating with a drug as powerful as aspirin.

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Alan
March 11, 2021 10:17 am

I’ve been taking low dose aspirin for years to fight high blood pressure. I’ve always been a big believer in vitamin C. So far during this pandemic I haven’t had a fever. Just glad Trump didn’t recommend vitamin C or aspirin, they’d all be banned.

commieBob
Reply to  Alan
March 11, 2021 12:15 pm

Annoyingly, it doesn’t matter what I take, I still get the occasional cough or the sniffles. I haven’t had a bad cold in years but I still get some of the symptoms. It makes me think I’m not completely protected.

Xinnie the Pooh
Reply to  commieBob
March 11, 2021 6:33 pm

coughs and sniffles are your body excreting pollutants

ozspeaksup
Reply to  commieBob
March 12, 2021 2:36 am

you want to have at least one cold or flu a year to keep the immune system geed up
Im dreading the next dose as ive had a yr without the prompt the body usually gets;-(

TonyG
Reply to  ozspeaksup
March 12, 2021 6:57 am

I’ve seen a bunch of people saying they’re going to continue with the masks, distancing, sanitizing, and other stuff even after C19 is gone. They say they “like not being sick” but have no understanding of how they could be weakening their immune systems. When they finally DO get sick they’re going to pay dearly for their choices.

Timo, not that one
Reply to  TonyG
March 12, 2021 9:23 am

Worse than that, not being exposed to pathogens does not stop your immune system from working hard. It just switches to attacking your own body when there is nothing else to do. We call these “auto immune diseases”.

commieBob
Reply to  Timo, not that one
March 12, 2021 5:22 pm

I believe it’s called the Hygiene Hypothesis. Of course, that should not be taken as an excuse for failing to wash your hands after you’ve mucked out the cow shed.

Greg
Reply to  ozspeaksup
March 13, 2021 1:57 pm

you do not need to fall ill with a cold or flu to be exposed to the pathogen and to stimulate an immune response. A strong immune system can be triggered and fight off the microbes without you needing to get ill to prove it.

Last edited 1 month ago by Greg
Chad W Jessup
Reply to  Alan
March 11, 2021 6:44 pm

What do you consider low dose, if you don’t mind me asking?

Steve
Reply to  Chad W Jessup
March 11, 2021 8:29 pm

I take baby aspirin which in Thailand is 80 mg. I also swallow (no chewing) a clove of garlic per day (but that’s mainly for gut health). Cannot remember last cold/flu.

Tom Abbott
Reply to  Steve
March 13, 2021 7:05 am

Garlic is good for your heart. It’s claimed it can dissolve cholesterol buildups, among other things.

Patrick MJD
Reply to  Chad W Jessup
March 11, 2021 8:50 pm

I take Cartia, low dose, 100mg per day, including mediation for blood pressure.

ozspeaksup
Reply to  Chad W Jessup
March 12, 2021 2:37 am

in Aus 100mg and get the coated ones to save your gut

Paul Penrose
Reply to  Chad W Jessup
March 12, 2021 10:41 am

I use the Bayer 81mg low dose aspirin, one every morning. At this level it is general considered safe, but it can still interact with other medications, so if you are taking anything else, you should ask your doctor.

Drake
March 11, 2021 10:21 am

So, like the world famous Harvard Nurses Study, they did not analyze all the OTHER things, like eating better, supplementing with D or C or?? or exercising more or eating more healthy or less that also goes along with someone who would take a daily aspirin for prevention even though they don’t have heart disease?

Science is crap these days but, per the referenced Harvard study, has been for many years.

Drake

Juan Slayton
Reply to  Drake
March 11, 2021 10:50 am

“They cross-referenced 10,477 results with medical records covering what preventive drugs patients take.”

….

“Results were adjusted to account for age and co-morbidities.”

There are a gazillion OTHER things that might be involved, but it looks to me like they analyzed the most obvious. Perhaps that was what motivated them to leave out the potential subjects who were prescribed baby aspirin _after_ a coronary event (like me).

MarkH
Reply to  Juan Slayton
March 11, 2021 1:30 pm

That reminds me of the recent bout of articles claiming that the new UK strain of COVID was “up to” 100% more deadly.

I tracked down the underlying study (https://www.bmj.com/content/372/bmj.n579) and found this paragraph quite interesting:

“Some of the increased risk could be explained by comorbidities. Information was not available about comorbid conditions in the data we analysed, although this would be partly controlled for by matching on age, ethnicity, and index of multiple deprivation. Currently there is no evidence of a mechanistic reason why people with certain comorbidities would be infected with one variant and not another. It is possible, however, that people with certain comorbidities are at a higher risk of infection with VOC-202012/1 and have a higher mortality rate. This would tend to reduce the hazard ratio attributable to VOC-202012/1 alone.”

hiskorr
Reply to  MarkH
March 11, 2021 1:53 pm

“Up to 100% more deadly” is certainly a scary way to put it, with an implication of “certain death!” What it likely means is a survival rate of 99.6% instead of 99.8%, etc.

Reply to  hiskorr
March 11, 2021 2:05 pm

I read here in Germany 68% more deadly

MarkH
Reply to  Krishna Gans
March 11, 2021 3:34 pm

Yep. The risk ratio was something like 1.64 (95% CI 1.3 – 2.04). The actual risk for either strain is very low though, particularly in the absence of comorbidities.

The news here (ABC Australia) choose to report the scariest figure.

Crispin Pemberton-Pigott
Reply to  hiskorr
March 11, 2021 2:57 pm

The range of “up to” includes zero.

ozspeaksup
Reply to  MarkH
March 12, 2021 2:39 am

yeah it sure hasnt shown ANY sign of easier caught etc in aus cases took 14days or more to develop and didnt spread to many

ozspeaksup
Reply to  MarkH
March 12, 2021 2:42 am

yeah it sure hasnt shown ANY sign of easier caught etc in aus cases took 14days or more to develop and didnt spread to many

March 11, 2021 10:25 am

WHO supports scientifically-proven traditional medicine
WHO recognizes that traditional, complementary and alternative medicine has many benefits and Africa has a long history of traditional medicine and practitioners that play an important role in providing care to populations. Medicinal plants such as Artemisia annua are being considered as possible treatments for COVID-19 and should be tested for efficacy and adverse side effects. Africans deserve to use medicines tested to the same standards as people in the rest of the world. Even if therapies are derived from traditional practice and natural, establishing their efficacy and safety through rigorous clinical trials is critical.

Artemisia annua – Pharmacology and Biotechnology
Artemisinin, a sesquiterpene lactone originally extracted from the medicinal plant Artemisia annua L., is an effective antimalarial agent, particularly for multi-drug resistant and cerebral malaria. However, the concentration of artemisinin in the plant is very low. Because the chemical synthesis of artemisinin is complicated and not economically feasible in view of the poor yield of the drug, the intact plant remains the only viable source of artemisinin production. Therefore, it is necessary to increase the concentration of artemisinin in A. annua to reduce the cost of artemisinin based antimalarial drugs. Plant scientists have focused their efforts on A. annua for a higher artemisinin crop yield. With the present volume, we are bringing together the research which is being done on this plant throughout the world and future possibilities for scientists and researchers who want to work on it

Finding that plant by Youyou Tu as anti Malaria drug was honored with the Nobel Price in 2015

Drake
Reply to  Krishna Gans
March 11, 2021 10:41 am

Even if therapies are derived from traditional practice and natural, establishing their efficacy and safety through rigorous clinical trials by transferring wealth from the end user to pharmaceutical companies is critical .

There, fixed it for them.





John Tillman
Reply to  Krishna Gans
March 11, 2021 10:44 am

Too bad WHO doesn’t support China’s fulfilling its obligations to other member nations by providing timely information, or releasing records, and letting foreign specialists into epidemic breakout areas.

Tu was lucky to survive the Cultural Revolution. Scientists were black-listed. She’s a Nobel Prize winner, but in China, one of the “Three-Withouts”, having neither a graduate degree, study abroad or membership in a national academy of science or engineering. Times were very different when she was 20 to 50.

Reply to  John Tillman
March 11, 2021 2:35 pm

At least the WHO acknowledged that PCR test with a threshold of 45 as mostly used was / is BS without further lookig for symptoms etc.

John Tillman
Reply to  Krishna Gans
March 13, 2021 3:49 pm

But too late.

ATheoK
Reply to  Krishna Gans
March 11, 2021 8:24 pm

Wormwood is antimalarial!?
Who knew…

Maybe Hemingway?
Absinthe and vermouth use wormwood/wormwood extracts.

Last edited 1 month ago by ATheoK
ozspeaksup
Reply to  Krishna Gans
March 12, 2021 2:41 am

its a related to wormwood but a tender annual not perennial
used widely in asia already for Malaria
hmm?
amazed cdc who and the pharmamobs havent banned it already

Last edited 1 month ago by ozspeaksup
Abolition Man
March 11, 2021 10:26 am

Kip,
Thank God President Trump didn’t have this study to cite! Imagine the dilemma the media and the DemoKKKrats would have been in trying to decide between the millions who take aspirin regularly and Orange Man Bad! It could have resulted in countless libtard heads exploding!
Fortunately, they felt no such qualms about banning or suppressing HCQ use, leading to possibly tens of thousands of needless deaths! I have often wondered why we didn’t hear more about ivermectin; was it’s use suppressed or was it just memory holed to allow more push for the vaccines that benefit Fauxi and his cronies!?

Curious George
Reply to  Abolition Man
March 11, 2021 11:31 am

Don’t even think of ivermectin.

Poems of Our Climate
Reply to  Curious George
March 11, 2021 12:12 pm

Hydroxychloriquine and zinc never stopped working, O ye of small faith.
They knock the crap out of this cold if you don’t let the virus build up.
H. should be in every grandma’s cabinet, like mecurocrome in the fifties.

Crispin Pemberton-Pigott
Reply to  Poems of Our Climate
March 11, 2021 3:00 pm

I can personally attest that chloroquine works. It is available over the counter in Canada. $40 for 100; 2 a day, five days.

Dyspeptic Curmudgeon
Reply to  Crispin Pemberton-Pigott
March 11, 2021 8:59 pm

Where in Canada? The Ford government in Ontario banned doctors from prescribing HCQ. My family doctor seemed scared feces-less to even *talk* about the possibility that it might help, even though she did agree that taking HCQ + zinc, as prescribed *would do no harm*. And she blanked completely on the efficacy of having adequate Vitamin D3 level.
She also basically refused to read about some findings about Vitamin C reducing effects, or curing other viral diseases, including measles and polio from 1947. Old == bad, seemed to be her position. Thinking of changing doctors but it is nearly impossible to do.

Comments about Vitamin D and Vitamin C in the last three items here:
https://catless.ncl.ac.uk/Risks/31/91#subj19

The Indonesian study referenced in Risks is now available here:
https://www.ultrasuninternational.com/wp-content/uploads/raharusun-et-al-2020_patterns_of_covid-19_mortality_and_vitamin_d_an_indonesian_study.pdf

The correlation between deficieny/adequacy of Vitamin D and the respective incidences of death is staggering. Basically 95%+ of deficient level patients died, while 95%+ of adequate level patients lived. There are many other peer-reviewed etc. studies about this correlation.
Vitamin D pills are cheap, as are aspirin. Gonna add aspirin to my daily intake.

Simon
Reply to  Crispin Pemberton-Pigott
March 11, 2021 11:02 pm

And I can personally attest to smoking 20 cigarettes a day. I have done it right through the covid thing and never got it. Or was it the billiards on a Friday night? Hmmm.

ozspeaksup
Reply to  Simon
March 12, 2021 2:45 am

all the uk reports showing smokers got LESS covid seem to have vanmished oddly enough
of course if smokers did get it they didnt all do so well
I’ll take my chances;-) and keep smoking
if nothing else it does keep people away, always a bonus

goracle
Reply to  Abolition Man
March 12, 2021 5:01 am

All the idiots on this site who hated on and maligned HCQ last year are just that… idiots. You idiots were part of the cabal that caused thousands more deaths that could have been prevented at the time if the HCQ w/ zinc regimen (that many doctors talked about as being beneficial when taken early) was not spat upon by you as if it was the leper of Covid symptom preventive medicines. Shame on you for spouting that rubbish and then claiming you’re not the science denier you claim others are regarding global warming.

Tom Abbott
Reply to  Abolition Man
March 13, 2021 7:20 am

“I have often wondered why we didn’t hear more about ivermectin; was it’s use suppressed or was it just memory holed to allow more push for the vaccines that benefit Fauxi and his cronies!?”

At first, Ivermectin was suppressed and deemed not applicable to the Wuhan virus by the National Instituties of Health, but now it has been approved for such use, but this information has not been widely circulated.

Today, any doctor can prescribe Ivermectin for the Wuhan virus, but you don’t hear this information from the News Media (other than Fox News).

If you want ivermectin or hydroxycholriquine, you can get it by going to myfreedoctor.com and filling out a questionaire which asks you if you have symptoms of Wuhan virus. Based on your answers, the doctors at that website will write you a prescription that includes invermectin, hydroxycholriquine, and prednesone.

The website asks for a donation, but you can enter $0.00 and they will fill your perscription anyway.

The perscription goes to your local pharmacist who fills it and you pay the regular price, so there is no chance of getting counterfeit drugs or being gouged on the price.

I have personal experiece with this and have this medication sitting in my cabinet right now.

And btw, there is a new medication entering a phase 3 trial that is said to stop the Wuhan virus dead in its tracks. In a few months, this may be available to the public. If it works like they say it works, then everyone can go back to normal activities without fear of the Wuhan virus or possibly all the corona viruses coming down the pike.

Last edited 1 month ago by Tom Abbott
RexAlan
Reply to  Tom Abbott
March 18, 2021 12:23 am

Well India is using Ivermectin.

India’s ‘miraculous’ ivermectin COVID treatment is only $3 per person

https://principia-scientific.com/indias-miraculous-ivermectin-covid-treatment-is-only-3-per-person/

March 11, 2021 10:29 am

Extract of medicinal plant Artemisia annua interferes with replication of SARS-CoV-2 in vitro
Researchers in the United States have shown that extracts of an aromatic herb called Artemisia annua inhibit the replication of severe acute respiratory coronavirus (SARS-CoV-2) – the agent responsible for the current coronavirus disease 2019 (COVID-19) pandemic.
Also known as “Sweet wormwood,” Artemisia annua (A. annua) is an herb from Asia that produces the antimalarial agent artemisinin.

Study

Last edited 1 month ago by Krishna Gans
John Tillman
Reply to  Krishna Gans
March 11, 2021 10:49 am

Related to the shrub from which absinthe is derived, A. absinthium. Artemisia species are common in the US West as different sagebrushes.

Reply to  John Tillman
March 11, 2021 2:37 pm

In earlier time, Absinth has been a deadly drink – and was prohibited for long time

John Tillman
Reply to  Krishna Gans
March 11, 2021 5:02 pm

Still isn’t good for your brain.

Reply to  John Tillman
March 12, 2021 6:58 am

A special treatment is necessary to make it drinkable.reducing Thujon.

yirgach
Reply to  John Tillman
March 13, 2021 2:34 pm

An occasional visit from the Green Fairy is good for perspective.
Ask Vincent.

Alex
March 11, 2021 10:39 am

I also have heard, olive oil taken rectal helps a lot against this china virus

Reply to  Alex
March 11, 2021 10:45 am

You don’t confuse it with castor oil ? 😀

Drake
Reply to  Alex
March 11, 2021 10:45 am

Hey, the only rectal for the China virus is the swab of O’Bidens new dip$hitlomats to China.

Tired Old Nurse
Reply to  Alex
March 11, 2021 11:10 am

Damn, I had a nice snarky reply about correlation all typed and then chickened out and deleted it.

Rory Forbes
Reply to  Alex
March 11, 2021 11:10 am

Yep … and it lubricates those anal swabs so many Chinese medics enjoy using.

Mr.
Reply to  Alex
March 11, 2021 1:49 pm

Probably like suppositories – for all the good they do me I may as well stick ’em up my arse.

curly
Reply to  Alex
March 11, 2021 2:29 pm

0W-20, full synthetic. can’t go wrong.

Doug Weedon
March 11, 2021 10:45 am

Funny how a couple of years ago they recommended to not take regular low dose ASA

Oldseadog
March 11, 2021 11:00 am

You need to be careful with aspirin though. I used to take aspirin before long flights and at the onset of a common cold, but since developing a kidney problem I have been told to avoid aspirin now.

Jake J
Reply to  Oldseadog
March 11, 2021 11:59 am

Can you say more about the kidney problem and aspirin? I ask because I had a kidney stone a couple years ago and would prefer not to repeat that, to put it mildly.

Oldseadog
Reply to  Jake J
March 11, 2021 1:28 pm

Jake, sorry, don’t know why my reply is above your question.

Reply to  Jake J
March 11, 2021 2:08 pm

I feel with you, I remember well….

Tom Abbott
Reply to  Jake J
March 13, 2021 7:37 am

Drink extra water to keep kidney stones flushed out of your system.

The best thing to do is drink about a 12-ounce glass of water every morning, on an empty stomach, which will flush your system of unnecessary byproducts of the functioning body. Drink room-temperature water, not cold water. This simple medical treatment goes back to the ancient Egyptians.

Your body chemistry may make you prone to kidney stones. You should get that tested.

Reply to  Tom Abbott
March 15, 2021 3:05 pm

I had 2 advices, move a lot and drink a lot. It was summer and nice weather, I was aged 23. Every whole day I was swimming in our lake drunk my bear at the beach kiosk, I had two 3 week certificate but no chance the stone moved out alone, the urologist finished that in 3 minutes, but back at work, I was asked about the holiday quality – bronzed as I was 😀

Last edited 29 days ago by Krishna Gans
Oldseadog
Reply to  Oldseadog
March 11, 2021 1:26 pm

Not a stone, reduced kidney function.

ATheoK
Reply to  Oldseadog
March 11, 2021 9:03 pm

That may be as a result of your kidney problem, not a cause of it.

Tylenol, Advil and ibuprofen damage kidney functions.

PaulH
March 11, 2021 11:10 am

There seem to be many things that can at least help with CV-19. Now if there were only something to help deal with the bad CV-19 policies created by health care bureaucrats and politicians.

 

max
March 11, 2021 11:17 am

Aspirin to be banned from use in the US in 3, 2, 1…

March 11, 2021 11:22 am

Blood thinner? That also seems likely.

RexAlan
Reply to  Shelly
March 11, 2021 3:14 pm

I have been taking a 100mg low dose Aspirin once a day for years now. My understanding is that it’s not a blood thinner but an anticoagulant. My friends all think Aspirin is a blood thinner too.

R Taylor
Reply to  RexAlan
March 11, 2021 4:05 pm

“Blood thinner” is colloquial term for anticoagulant.

ozspeaksup
Reply to  Shelly
March 12, 2021 2:48 am

yes same as theyre using Heparin and a nasal spray heparin product as well(aussie doc promoted the nasal spray but got little follow up)

March 11, 2021 11:36 am

I doubt this study result is real.

Low dose aspirin has no effect on related respiratory viruses including common cold coronaviruses—no change in cold or flu incidence. Why then COVID19?

As posted here last year, HQC has two mechanisms of action. Neither is anti-inflamatory. As an antiarthric, it raises cytosol pH, causing lysosome ‘leakage’, reducing the cell surface displays triggering the autoimmune attack. Same mechanism alters the surface receptor used by the ovid spike protein, making the cell less susceptible to infection. As an antiviral, it is a zinc ionophore, so when taken with zinc elevates cytosol zinc levels that inhibit viral replication.

Butesnoside just reduces the cytokine storm associated with severe symptoms and hospitalizations. Works the same as dexamethasone (another old steroid) preferred in the US.

I doubt antiinflammatories per se are the trick. If they were NSAIDs like ibuprophen would work, and they apparently don’t.

Reply to  Eric Worrall
March 11, 2021 3:08 pm

Eric, I did not intend to criticize your good post catch on this new Israeli paper, only the surficial anti-inflammatory connection speculation. I agree with your response. And surely, the known aspirin blood thinner effect reduces somewhat the COVID19 microclotting symptom I wrote about last year.
The Israeli paper problem is, that those symptom appears in less than 1/3 of NYC autopsies, yet they claim a 39% reduction. Might be within margin of error, dunno. Sketchy from first principles. Regards.

guidoLaMoto
Reply to  Rud Istvan
March 12, 2021 2:32 am

Also, don’t confuse Absolute Risk Reduction (ARR) with Relative Risk Reduction (RRR)– used to turn unimpressive single digit per cents into impressive double digit per cents. …A risk of !/3 reduced by a RRR of 1/3 (Wow!) is only an ARR of 1/9 (BFD).

whiten
Reply to  Rud Istvan
March 11, 2021 1:03 pm

With all due respect,
All you put forward in your comment is plain garbage.

Please try to read and learn properly the history of Aspirin.

Strangely enough you will find out that Quinine and Aspirin are the most closest medicines, “sisters”, belonging in the same class, anti-fever drugs,
in some given cases the most potential and effective.anti fever drugs there to be.

But you got to dig first in the history of all that beauty, with no silly biases.

cheers

John Tillman
Reply to  Rud Istvan
March 11, 2021 1:59 pm

Painkillers like aspirin, ibuprofen and acetaminophen can relieve cold- and flu-related symptoms such as headache, earache and joint pain. They can also lower a fever.  Makes perfect sense that they could treat COVID.

Aspirin is more than just an anti-inflamatory. I happened to be interviewing Joshua Lederberg right after the discovery of how aspirin works was published. He told me about it.

John Tillman
Reply to  John Tillman
March 11, 2021 2:30 pm

Drom your alma mater:
https://www.health.harvard.edu/diseases-and-conditions/treatments-for-covid-19

Is it safe to take ibuprofen to treat symptoms of COVID-19?
Some French doctors advise against using ibuprofen (Motrin, Advil, many generic versions) for COVID-19 symptoms based on reports of otherwise healthy people with confirmed COVID-19 who were taking an NSAID for symptom relief and developed a severe illness, especially pneumonia. These are only observations and not based on scientific studies.
The WHO initially recommended using acetaminophen instead of ibuprofen to help reduce fever and aches and pains related to this coronavirus infection, but now states that either acetaminophen or ibuprofen can be used. Rapid changes in recommendations create uncertainty. Since some doctors remain concerned about NSAIDs, it still seems prudent to choose acetaminophen first, with a total dose not exceeding 3,000 milligrams per day.
However, if you suspect or know you have COVID-19 and cannot take acetaminophen, or have taken the maximum dose and still need symptom relief, taking over-the-counter ibuprofen does not need to be specifically avoided.

Last edited 1 month ago by John Tillman
Mr.
Reply to  Rud Istvan
March 11, 2021 2:25 pm

NSAIDs like ibuprophen would work, and they apparently don’t.

Now you tell me. Just as I got back from London Drugs with my weekly supplies ):



pills.jpg
Crispin Pemberton-Pigott
Reply to  Rud Istvan
March 11, 2021 3:10 pm

Rud:

“…has no effect on related respiratory viruses including common cold coronaviruses—no change in cold or flu incidence. Why then COVID19?”

That is not difficult to trace. See the set of videos from MedCram for the full biochemical explanation, perhaps starting around number 43 or 45. COVID-19 is not primarily a respiratory disease, it causes the body to attack itself and the lungs are collateral damage. Common colds are lung-related.

COVID is a disease of the epithelial cells which is why there are blood clots, heat attacks, strokes and complex interference in the lungs. The shortness of breath is largely due to a cytokine storm and if you have one, it is already too late for most people. The main issue is the ACE2 receptor – what gets to it first. COVID has to grab hold of the ACE2 receptors of epithelial cells, for which is highly tuned. There are many ways to block that. Putting zinc into the cell is one way. Changing the Ph works, and so does the group of anti-inflams like Invermectin and Colchicine (found to be totally effective in Quebec).

Doug Sloan
Reply to  Crispin Pemberton-Pigott
March 12, 2021 3:55 pm

A related issue is the role of the TMPRSS2 receptor, interaction with which being required before the virus latches on to the ACE2 receptor. Apparently it interacts with that furin cleavage site.
The drug Bromhexine blocks this interaction in the test tube by grabbing onto the TMPRSS2 receptor. It has greatly reduced the illness and mortality from Covid-19 in at least one, admittedly small trial.
Bromhexine is a decongestant, mucolytic and expectorant. It is over-the-counter in most countries where it is sold. Off-patent, safe and incredibly inexpensive.

guidoLaMoto
Reply to  Rud Istvan
March 12, 2021 2:25 am

Everyone is different– a point the advocates of socialized medicine just can’t seem to understand.

Don’t confuse “doesn’t work” with “doesn’t work for everyone.”

Those who get really sick with CoVoD are those who experience the cytokine storm…

.Our immune systems are set up like a remodeling contractor operation– a demolition crew precedes the installation crew and the logistics need to be well co-ordinated. We don’t want the demolition crew working too fast or casing excessive collateral damage..

.But that is what happens with cytokine storm, so any remedy that tends to inhibit the immune response should tend to inhibit that phenomenon. In fact, all the typical symptoms of viral infection (fever, malaise, myalgia) are cause by our immune reaction to the vial presence– mostly due to secretion if interferon..

Peta of Newark
March 11, 2021 11:39 am

I came upon the ‘Aspirin Story’ just very recently

IF YOU ARE ON ASPIRIN NOW – GIVE IT UP THIS MINUTE

and just wow.
The story had everything..

It started with autopsies of heart attack victims in the 60’s
And there was/were Blood Clots

Aspirin was widely known to slow/prevent/alleviate clotting so BINGO!
There it was.
Give people Aspirin = no more clots = no more heart attacks
(Is that in any way familiar to the notion of CO2 ‘trapping heat’)

In due course a trial was set up, in the UK.
The results were dismal. Perfect fail
There were a few less fatal heart attacks but overall, MORE people died.
From uncontrolled internal bleeding

But, this was an uncontrolled study among ordinary folks. Everyone knows what a shifty, untrustworthy and mendacious bunch they are.

So they did another UK study except with real actual doctors keeping an eye on things.
Same dismal results
Less heart attacks but again, More People Died

So the studying was taken to the US.
Both an informal study and a 2nd one under medical control.
Same dismal results again both times.
Aspirin was a killer

Do a search, right now, for its LD50 – it really is hideous stuff

The studying returned to the UK and after some mumbling and muttering about ‘dosage’, was re-run.

This 5th time, they got the result they wanted.
The one that they KNEW from the very start.
(Magical Thinking on ‘Speed’ or what)
A lot less heart attacks. Similar numbers died from bleeding but overall:
Lives Were Saved By Taking Aspirin

[Just like Statins are craiced up nowadays. The test result made front-page news along with statements saying that *everyone* should take Aspirin every day.
If your Alarm Bells ain’t ringing now – sigh]

It took a lot of digging and it came out of the Stomach Bleeds that Aspirin causes.
The assumption was made that the acidic Aspirin was upsetting the stomach walls and causing the ulcers & bleeds

So they added stuff called Bufferin to the Aspirin – to supposedly neutralise the acid – and this mixture is what worked to reduce the number of fatal & non-fatal heart attacks..

Now then, if you’ve been reading my ravings in these parts, you will have seen /heard me carrying on about Magnesium.
An insanely important neuro-transmitter

Something really rather important for something such as your heart would you not think
If you run out of magnesium, even for a a hour or less – You Are History.
OK ok, you may survive but, only in the way that cabbages survive.

And Bufferin was/is made from Magnesium

The extra Mg in the Aspirin pills used in the 5th trial, the one that worked and even just a tiny amount, was what was saving those lives.

Epsom Salts are your friend – the most significant componenet of the water at Health Spas all around the World since forever.
Drink it, swim and bath in it. Whatever

Epsom Salts (Bittersalz) is/are your friend to fend off Heart Attacks, Blonde Moments AND Dementia

Take it or leave it…………..
if you take too much, you just pee it out the very next day.
(I think it manifests as stuff called Struvite, an epic plant food. Pee on your garden, let’s have some Global Garden Greening eh why not?
Do watch out for those bastid nosey-parkering Sputniks tho. haha
😀

Last edited 1 month ago by Peta of Newark
Poems of Our Climate
Reply to  Peta of Newark
March 11, 2021 12:04 pm

Correct. Aspirin is a harmful as helpful. Mortality rate FACT. Not worth taking.

People are generally low in Magnesium, FACT.
And in vitamin D.

Scissor
Reply to  Peta of Newark
March 11, 2021 4:46 pm

There are some that say magnesium can be taken transdermally and thus avoid GI troubles. But this review indicates they aren’t certain and recommend additional study.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5579607/#:~:text=Prolonged%20soaking%20in%20Epsom%20salts,mL%20after%20the%20first%20bath.

ozspeaksup
Reply to  Peta of Newark
March 12, 2021 2:55 am

take too much magnesium especially as epsom salts and be running to the loo!
we use it for colic horses and the “end result” can be explosively good;-)
magnesium citrates well absorbed btw
for interest in magnesiums protective uses see Dr Sircus.com

littlepeaks
March 11, 2021 11:51 am

I’ve been taking low-dose aspirin for years now. They accidentally found out that I had two large blood clots where my vein from my leg enters my abdomen. After treating me with blood thinner for a year, my doctor told me I should take aspirin for the rest of my life. They had no idea what cause the blood clots because I’m into running — I probably had no symptoms because I have large veins.
Before that, I use to take three baby aspirins a day for my heart. The doctor asked me why I did that, and I told him it was because I liked the (orange) taste. His eyes got real big, and told me not to do that any more.

Jake J
March 11, 2021 11:55 am

We got the first Pfizer shot on March 3 and will get the second one on March 24. My other half had no side effects at all, while I had a sore arm for a few days, and mild “flu-like” symptoms: achy, a bit of congestion.

I was wary of interfering with the development of antibodies, but I decided to use Airborne (zinc, Vitamin C) and aspirin and 1000 IUs of Vitamin D, which is what I’ve always used for head colds except for the Vit D. Airborne + aspirin has always cut the severity of my colds in half, and it worked well with the vaccine. As for aspirin side effects, I chuckle a bit about that because Tylenol is much more dangerous.

Last edited 1 month ago by Jake J
Clyde Spencer
March 11, 2021 12:00 pm

The unanswered question is, “Why have so many drugs — at last count about three-dozen — shown efficacy in treating COVID-19?” There is a lot that we still don’t know about this disease!

HCQ has been a highly contentious topic on this forum. It strikes me that politics plays a larger role, on both sides, than the actual science. The most recent news is the following:
https://scitechdaily.com/the-end-of-hydroxychloroquine-as-a-treatment-for-covid-19-year-of-madness-capped-by-trial-showing-drug-has-no-benefit/

Poems of Our Climate
Reply to  Clyde Spencer
March 11, 2021 12:26 pm

There are some twenty studies showing it works. It worked on me. Not spending twenty bucks and having it in your cabinet is insane. It likely works on most colds and flu’s, to minimize. There are many suppliments and drugs that knock covid down to size before it can ever get to dominate in the lungs.

Your gubmint is training you by controlling the solution to this minor disease. Anyone who wants them can have use the multiple solutions available. Trump wimped out and should have fired Fauchi. Instead, take a look at the vaccinated, submissive mask people, walking the streets. We are all a little dumber for our submission.

Pamela Matlack-Klein
Reply to  Clyde Spencer
March 11, 2021 12:53 pm

Unfortunately, most of the trials used HCQ too late or too much, and without zinc and Z-Pac. All the trials showing good results are observational only and thus discounted by practitioners. BUT it was the observational trials that used the full protocol and achieved good results.

Derg
Reply to  Pamela Matlack-Klein
March 11, 2021 1:16 pm

Sprinkle the HCQ on the patient right before they died “see the sh1t doesn’t work.”

🤓

Paul C
Reply to  Clyde Spencer
March 11, 2021 1:00 pm

Yet many of the trials set up with treatment protocols that were claimed to work appear to have positive outcomes – similar efficacy to the vaccine trials. There is a great deal of suspicion about trials such as the one you show above which are funded by vaccine investors, and appear to be aimed at eliminating the competition (of prophylaxis, or safe, cheap, alternative treatments).
https://c19study.com/

Gary Pearse
Reply to  Clyde Spencer
March 11, 2021 11:14 pm

Clyde, I frankly don’t trust the medical pharma industrial NWO complex. To call HCQ highly dangerous is a poker ‘tell’ to a guy who has, along with a billion other people, taken it since the 1960s as an anti-malarial. And to know that not to take it killed hundreds of millions of Africans.

A ‘study’ in UK (Oxford?) and a few other places criminally used massive overdoses of HCQ (1800mg/day) to ‘show it doesn’t work and big Lancet and American Medical journal articles panning the drug had to be withdrawn sometime after they had succeeded in having the drug banned in a number of states and in France.

Yes it does have some side effects but no medical double blind test of a couple of hundred patients can compare to the trillions of doses successfully administered over a century to assess the dangers of its use. And in Europe and America it has been prescribed to millions of elderly arthritis and lupus patients. It is the definition of a “no regrets” pill. A lethal dose of milj will kill you Clyde.

Paul C
Reply to  Gary Pearse
March 12, 2021 10:02 am

The badly designed “RECOVERY” trial which used a massive overdose on hospitalised (i.e. already sick) patients can be interpreted to indicate the success of HCQ at treating COVID-19. As the overdose must have had negative consequences for some patients, the overall results being neutral, actually indicate that there must have been significant benefit in those patients who survived the deliberate poisoning. Treated early, using the full protocol with doses used successfully on the front lines, how many souls might have been saved.

Paul C
March 11, 2021 12:26 pm

Chloroquine/Hydroxychloroquine were also over the counter medicines in the UK, and I think they technically still are. However, an instruction was given to pharmacists about a year ago that dispensing OTC for COVID-19 would invalidate their professional insurance, effectively making them prescription-only.

gringojay
Reply to  Paul C
March 11, 2021 1:29 pm

Our betters assert they are only looking out for us.

B0565A76-F8C4-4C6D-93BD-1F20C30DB7EB.jpeg
Scissor
Reply to  gringojay
March 11, 2021 4:51 pm

A lot of chair lifts today are basically still like that though in beginner areas safety bars that come down above the lap are common too.

john
March 11, 2021 1:19 pm

Once you move away from double blind studies uncertainty grows and grows, until you reach a point where you can believe anything you want.

This blog has promoted expert analysis, that said robust studies showed we reached the Herd Immunity Threshold some time late last Summer.

That prediction, supported by so many here, was a total load rubbish. It would be best if watts up with that left Covid alone, if we want to preserve a semblance of sanity.

The 1st wave didn’t touch me but I lost relatives and close friends to the 2nd wave, unfortunately Professor Witty was right and this blog was wrong.

John Tillman
Reply to  john
March 11, 2021 2:09 pm

Would you please be so kind as to link to a comment saying that herd immunity was reached last summer? Thanks.

Many argued that lockdowns were unnecessary and harmful, except for the most vulnerable, who needed preventative, protective quarantine, with caregivers suited up. Data now support that conclusion. There was no need to close schools.

Model projections were way off because they confused CFR and IFR, and the latter was unknowable. Hence the computer games were worse than worthless, like GIGO GCMs.

Granted, Western governments were flying largely blind, because the CCP lied, covered up and wouldn’t let foreign specialists into Wuhan. The enemies of humanity in Beijing still haven’t released data from Wuhan and its Virology Institute.

gringojay
Reply to  john
March 11, 2021 2:12 pm

Hi john, – The USA Dr.Fauci, who has been telling Americans what to believe about this Wuhan virus yesterday, Wed. 10 March 2021, said the following on the internationally distributed news channel CNN.

Quote: ” When you don’t have the data and you don’t have the actual evidence, you’ve got to make a judgement call.”

This man, Fauci, has precipitated significant national sacrifices that citizens, at the very least, have the right to think critically about & discuss. I, for one, would not advocate silencing WUWT blog commentators who did not “have actual evidence” and didn’t “have the data” about herd immunity. I address this since some of Dr.Fauci’s protocol(s) in retrospect seem unsupported (case in point death percentage comparing Florida state & California state with different degrees of adherence to Fauci-ism) indicates Dr.Fauci apparently “was wrong” sometimes.

While I think you know this, I’ll close mentioning that herd immunity to viral pathogens does not mean no additional people die from that virus once herd immunity is achieved.

9DF9EA15-9458-4850-A314-3CFD34D4889F.jpeg
Last edited 1 month ago by gringojay
Drake
Reply to  john
March 11, 2021 8:45 pm

John,

You wrote your comment a long time ago. A typical leftist straw man argument. Put BAD words in another person’s mouth, then say how bad they are.

Where are the posts you referenced? Not their, I didn’t think so.

Go watch Madcow, you know, get the “truth”. Russia! Russia! Russia!

John F Hultquist
March 11, 2021 1:36 pm

Low dose aspirin in the USA is 81 mg.
I guess the babies are bigger.

This is one chemical the body can get a bit used to, so no longer does what folks think it is doing.
Although this is the first I’ve heard of it killing critters, so that might not have the same character.

March 11, 2021 2:09 pm

Eric,
“Surely this coincidence of independent claims that three unrelated powerful anti-inflammatory drugs are therapeutically effective against Covid-19 is worth someone in the medical community taking a closer look.”
 
 They have, of course. And dexamethasone has been part of standard treatment for many months now, and has been credited with strongly assisting recovery. 
https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(20)30503-8/fulltext

Dex is a more effective antiflammatory than the others mentioned. Trump took it when he had Covid

He did not take HCQ.

Last edited 1 month ago by Nick Stokes
Poems of Our Climate
Reply to  Nick Stokes
March 11, 2021 4:40 pm

Donald J. Trump took HCQ before he caught the coronavirus. We don’t know how long or how many doses. HCQ builds up in your system and it is reasonable to consider its protective capacity. HCQ free Afro-European Americans are messed up pretty bad on this virus, yet the pure Africans in malaria zones are not succumbing to the disease.

Last edited 1 month ago by Poems of Our Climate
Clyde Spencer
Reply to  Poems of Our Climate
March 11, 2021 5:27 pm

Donald J. Trump took HCQ before he caught the coronavirus.

Not what I would call a sterling recommendation!

David A
Reply to  Clyde Spencer
March 12, 2021 3:27 am

He had stopped taking it well before he contacted the Wuflu.

There are dozens of studies that show the effectiveness of HCQ, administered correctly in combination with zinc.

India, with 12 times the population density, and millions practicing zero social distancing ( dozens to hundreds sharing one toilet) and about plus 40 million people then the US over the age of 65, has less then 10 percent of the US death rate.

Observer
Reply to  David A
March 14, 2021 8:38 am

India has a very different age demographic. Also, the average Indian who makes it past 50 is probably far fitter immunologically than the average Westerner.

Tom Abbott
Reply to  Clyde Spencer
March 13, 2021 7:59 am

The residual effects of taking HCQ as a preventative measure are claimed to last about 30 days.

Trump got infected more than 30 days after he stopped taking HCQ.

Trump received the Regeneron cocktail and Remdisivir as his main treatment for the virus.

March 11, 2021 2:28 pm

An Israeli doctor has reported good results with treating patients with hyperbaric conditions – a room with high atmospheric pressure and high O2 content as an anti-aging treatment. A patient would spend maybe an hour or so per day in the room. It would be interesting to know if there is any anti Wuhan Virus effect but it is not easy to experiment with treatments for a potentially deadly disease.

Paul C
March 11, 2021 4:16 pm

Good results with providone-iodine mouthwash too. The stuff got effectively banned in the UK because of EU rules about a decade ago, but it would certainly be worth a low-risk gargle with betadine at the first sign of symptoms in those countries that still sell it.
https://c19pvpi.com/

John Tillman
Reply to  Paul C
March 11, 2021 4:52 pm

Nasal spray and mouthwash are effective against COVID.

So if Trump had used some term other than injecting bleach, he’d have been right.

Not that injecting bleach necessarily hurts you. Junkies whom share needles often end up with chlorine in their blood.

Last edited 1 month ago by John Tillman
Tom Abbott
Reply to  John Tillman
March 13, 2021 8:02 am

“So if Trump had used some term other than injecting bleach, he’d have been right.”

I don’t recall Trump ever saying “injecting bleach”. I recall the Leftwig News Media claiming that’s what he said, but they are distorting his words.

TonyG
Reply to  Tom Abbott
March 13, 2021 9:21 am

I would like to see actual evidence of Trump saying to inject bleach. So far nobody seems to have turned any up.

John Tillman
Reply to  TonyG
March 13, 2021 3:54 pm

Really? “Injecting disinfectant” is all over the Internet:

TonyG
Reply to  John Tillman
March 13, 2021 4:44 pm

BLEACH

John Tillman
Reply to  TonyG
March 13, 2021 5:04 pm

Bleach was the disinefectant under discussion at the time. Which disinfectant do you suppose that Trump had in mind?

I voted for him. I’ve pointed out to friends that mouth wash and nasal sprays involving chlorine have proved effective, and that our water is chlorinated, adn that junkies often inject some bleach from reused needles. But the fact remains that DJT did suggest injesting disinfectant.

Observer
Reply to  John Tillman
March 14, 2021 8:43 am

… but not “bleach”.

Was he talking about ozone therapy? Who can say? The fact is he’s an inarticulate, ignorant, narcissistic blowhard who should have kept quiet and not have given the Democrats and media such an easy target.

And I say that a someone who would have voted for him in 2016 and 2020.

Tom Abbott
Reply to  Observer
March 15, 2021 6:50 am

Trump isn’t ignorant and the Leftwing News Media distorts everything Trump says, so you are basing your “inarticulate” on leftwing interpretations of what Trump said.

If you actually listen to Trump’s words without interpretation, you will find Trump is very articulate.

Trump is not a blowhard, he accomplishes what he sets out to do.

I like Trump’s blunt style. It’s perfect for the liars in the Leftwing Media. Trump drove the Leftwing News Media’s approval ratings down to the level of used car salesmen.

That’s a good thing. Maybe the most important thing Trump did . He exposed the Leftwing Media for the blatant, partisan liars that they are.

I hope you vote for Trump in 2022, or 2024 or whenever he decides to run. I look forward to the consternation this will cause among the radical Democrats.

Last edited 29 days ago by Tom Abbott
Reply to  Paul C
March 12, 2021 6:08 am

I sometimes use hydrogen peroxide as a mouthwash….you can rinse with water afterwards if you are concerned with a little bit swallowed. The effectiveness of anti-bacterial handwashes showed bacteria can recover within hours….must hide in skin pores or new bacteria colonize from the air or from touching surfaces.

Last edited 1 month ago by Anti-griff
Tom Abbott
Reply to  Anti-griff
March 13, 2021 8:07 am

I don’t use anti-bacterials. I wash with plain water. And I haven’t had a cold or the flu in at least several decades. Over the course of those several decades, I did pay special attention to washing my hands everytime I handled something that was handled by someone else and I think that is probably why I haven’t had colds and the flu. I get flu vaccinations sporadically. Haven’t had one in several years.

Stevek
March 11, 2021 4:55 pm

There is a new drug in trials that apparently stops Covid in its tracks. Unfortunately it is a mutagen drug so you may get cancer.

William Haas
March 11, 2021 5:32 pm

Besides being an anti inflammatory, aspirin thins the blood where as a Covid 19 infection thickens the blood. I would think that if the circulatory system does not work well everything else does not work well including your bodies ability to fight off the infection. I am not a medical doctor.

Tom Abbott
Reply to  William Haas
March 13, 2021 8:13 am

Doctors have been trying a new, repurposed drug to treat the Wuhan virus. Its generic name is Tricor.

Tricor reduces the fats flowing in the bloodstream, and one study claims that when the Wuhan virus attacks the lungs it changes how the lung cells behave. Normally, the lung cells will expel fat from within themselves, but the Wuhan virus causes these fats to stay in the cells and build up and this diminishes the amount of oxygen the cells can take in.

This particular study used Tricor to rid the lungs of these fats and patients treated this way had very good recoveries from serious lung/breathing problems.

Fran
March 11, 2021 6:00 pm

This kind of study is always problematic because those who regularly take anything for preventive maintenance are different from those who do not. They will also be eating better and doing their walks, and more likely to be taking appropriate vitamins. I also see no indication that they controlled for social class/education in the abstract above.

The most common reason for prescribing ASA these days is the presence of a stent. Its use to ‘prevent’ heart disease has entered popular mythology. However, the cost benefit ratio is iffy –

‘Estimates of absolute rates of harm from aspirin use, per 100,000 patient-years of follow-up, were 99-178 for non-trivial bleeds, 46-49 for major bleeds, 68-117 for GI bleeds and 8-10 for haemorrhagic stroke.’

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4781046/

ozspeaksup
Reply to  Fran
March 12, 2021 3:03 am

I had to halt grape seed extract and tumeric before surgery as the surgeon decided the thinned blood(yes they stop clumping redcells) which is why i rarely take the daily heart aspirin- prefer the naturals, and after week without them my RA also reminded me why I bother doing the more expensive daily supplement pathway

Last edited 1 month ago by ozspeaksup
lee
March 11, 2021 6:03 pm

In the Australian papers today is a report that Astra-Zeneca may cause blood clots. Perhaps aspirin may be effective.

Xinnie the Pooh
March 11, 2021 6:33 pm

Look up what happened with the American Army created “spanish” flu that originated at San Francisco barracks – aspirin ended up killing thousands

whiten
Reply to  Eric Worrall
March 12, 2021 1:15 pm

Do not mean to nitpick, but just for the sake of saying it.

As I understand it the clause “highly toxic” does not match or do justice to aspirin overdosing.

The proper clause or term should be “highly poisonous”, meaning; very very unlikely to be toxic.

Highly pure efficient poisonous substances can not be or considered toxic.

cheers

whiten
Reply to  Xinnie the Pooh
March 12, 2021 1:01 pm

And then plain brains do not understand that the death cause listed there was not flu, but aspirin poisoning.

You see neither aspirin or HCQ treatment guaranties recovery of already done damages.

If one happens to be beyond point of no return, it remains there with no chance of return to life, even when drugs like Aspirin and HCQ may do a proper arresting of the initial problem causing such deep damages in the first place

The death of thousands you point at was listed as aspirin poisoning as the symptoms associated with the death were clearly poisoning by aspirin, aka a painless end.
These thousand deaths were non changeable, at the given point…
already beyond point of no return.
The aspirin treatment there makes only one difference… painless death.

Meaning that many more, like up to hundred thousands others, ended up saved by aspirin treatment at some very critical health condition.

There is no any drug that will bring one back to life, when one already beyond point of no return… and still even at that, aspirin in high dose treatment may give a painless passage to the last mile… at the very least.

cheers

Richard
March 11, 2021 7:39 pm

Not as big of a reduction as HCQ.

Patrick MJD
March 11, 2021 8:48 pm

Do not take aspirin without consulting your doctor – aspirin use, even in small doses, can have nasty and sometimes fatal side effects.”

Consult your Dr. YES, but PUHLEASE lay off the fatal risks quotes. Some people are at risk, as with ANY drug, but in general very miniscule. I have been taking it for years to thin my blood for hemochromatosis and other blood related complications.

Gary Pearse
March 11, 2021 10:20 pm

…somewhere out there is a cheap, generic anti-inflammatory which is even more effective than the claimed effectiveness of Butesonide, just sitting on a shelf somewhere waiting for some doctor to notice it.”

Tonic water may be just what you suggest. Chloroquine from a tree bark in South America and another tree in Africa was used by indigenous folk for malaria. Spanish colonists reported on its use in the 17th century. The famous gin and tonic was the pleasant way that the British took their daily antimalarial dose before it became a popular cocktail.

Oh, and BTW, ‘aspirin’ was long used by North American native people as an anti-inflammatory and therapy for headache. It is extracted as a tea made with the underbark of the willow tree and possibly poplar. Ive chewed the underbark and the aspirin flavor is unmistakable.

My far flung family took to gin and tonic as a preventative under my suggestion (they added the gin part!) after one of my daughter’s families got Covid in UK. I had hydroxychloroquine tablets ready yo use as a reserve left over from a trip to Minas Gerais, Brazil.

I have been criticized (even here at WUWT) for my doing this by people who believed the lies from the totalitarians and greedy pharmacy investment beneficiaries about how dangerous this drug is! Hell, I’ve used the drug since the 1960s in Africa and recently in Brazil as have perhaps over a billion people. I dare say that of all my colleagues, and neighbors in these countries I never heard of a debility or death from it.

Add millions of lupus and arthritic users of it and there, my friends, is something vastly superior to any double blind study of a few hundred patients. Yes, there are side effects known. And there are side effects of not using it as hundreds of millions of deaths from malaria attest. Ya know, a lethal dose of milk will kill you.

Doc Chuck
Reply to  Gary Pearse
March 11, 2021 11:47 pm

Just a further word of caution — every one of those original passengers landed from the Mayflower who ate some turkey that first Thanksgiving (if I may so dare now to mention that increasingly politically incorrect celebration) is dead today. Do be careful out there!

whiten
Reply to  Gary Pearse
March 13, 2021 3:31 am

White willow bark “pouder” extract, the very first medicine discovered produced and used as the european equivalent of quinine, an anti fever drug, the “same” medicine as the later day Aspirin,
is still produced and in sale.
The earlier and first organic bio form of Aspirin.
The capsules quite equivalent to “baby” low dose of aspirin.

The “medical package” extracted and utilized is naturally made, simply extracted by man.
Far stable and more balanced than the fossil fuel mass produced aspirin.

Not as potential and punchy as the highly concentrated aspirin,
and with no any side effects in it’s own.

Aspirin was not discovered or invented, simply happens to be a product of an attempt to achieve feasible large mass production of the same White Willow bark extract medicine in an industrial scale, from non bio source substances.

cheers

Eric Vieira
March 12, 2021 12:55 am

Another aspect which wasn’t discussed here: low dose aspirin has well known platelet aggregation inhibiting effects, and thus anti thrombotic properties. Roche stopped development of a platelet aggregation inhibitor in the clinic, because it wasn’t able to significantly beat the much cheaper low-dose aspirin. This adds to the anti-inflammatory effects. Both inflammation and blood clots are some of the worst effects of COVID-19. Many people were also helped when the lungs were attacked, by treatment with anti-inflammatory asthma sprays.

ozspeaksup
March 12, 2021 2:34 am

Butesonide IS the cheap version
if you buy branded symbicort(same drug) pay 3x or more
doing other research for personal reasons i see that pharmas buyups of older meds and the 400% or more hikes wasnt just for epipens
a wormer with anticancer properties went from 100 to 400 and then became totally UNavailable in usa.
having issues finding bulk supplies here but small volumes are just 9$ otc

richard
March 12, 2021 4:11 am

Has to be a lot better than taking the vaccine as the NHS guide illustrates- there is no cure for Covid and they don’t know whether the vaccines stop you catching or passing on the virus- some testing! Probably the give away is all tested vaccines up until 2020 were rejected where as the untested vaccines from 2020 were rolled out.

Coach Springer
March 12, 2021 7:44 am

Do not take aspirin without consulting your doctor – aspirin use, even in small doses, can have nasty and sometimes fatal side effects.” This seems like news to me. Is it anything like drinking too much water?

Sweet Old Bob
March 12, 2021 8:46 am

Senior USAF Doc who administered my second Moderna shot , observing my SSN cap , quietly told me that if I was going to take something for pain after the shot , to take Tylenol , not aspirin because aspirin would reduce the effectiveness of the shot .
Docs see certain things that they don’t go public with …

Ulric Lyons
March 12, 2021 9:05 am

I treated my suspected covid-19 infection in January 2020 with aspirin, before we had news of the virus. But the very first negative news that I heard about any drug for treating covid-19, was a report from supposedly from China which said that aspirin was unhelpful and dangerous for covid-19 patients. Meanwhile we’ve had this Chinese report for a year.

Protective Effect of Aspirin on COVID-19 Patients:https://clinicaltrials.gov/ct2/show/NCT04365309

Cliff Hilton
March 12, 2021 11:30 am

I take 325 mg Aspirin, daily, due to CABG 11/2019. No other comorbidities. Got CCP virus 10/2020. Lost taste and smell. Weak one day and fine all others. No cough. Little fever. Didn’t help me. Maybe too high of dose or just not one of the lucky 29%.

Robert J Frailey
March 12, 2021 2:39 pm

I acquired covid from a coworker for Christmas. At onset and during the infection I was consuming two aspirin and a Benadryl mornings and evenings for 15 straight days. My symptoms were minor, sinuses draining, minor cough, fever for one day, no smell or taste for months and got tired easily. Had positive tests for three months, finally passed it. Aspirin works well for me.

R.A.
March 12, 2021 2:56 pm

It is true that Aspirin is a powerful drug, that should be used with care. It can be a cause of intestinal bleeding for example, which is a “go to the emergency room” condition–as I know from personal experience.

In general, it appears that anti-inflammatory medicines are useful in treating Covid, which is something we should be investigating further.

Greg
March 13, 2021 1:53 pm

My French friend told me hydroxychloroquine was a non-prescription over the counter medication in France, until President Macron banned it in early 2020, to stop people self medicating to treat their Covid symptoms.

No, it became a prescription drug in France in October 2019 (per Prof Raoult). There were already moves to suppress this cheap and patent free drug before Covid became an issue.

Last edited 1 month ago by Greg
March 14, 2021 3:27 pm

Please watch this and form a judgement.
Peter McCullough, MD testifies to Texas Senate HHS Committee 
https://youtu.be/QAHi3lX3oGM

 

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