Guest Post by Willis Eschenbach
A couple of days ago, I got to looking at the daily record of US deaths from the coronavirus. It’s shown in Figure 1 below:

Figure 1. US daily deaths. Created on May 5, but shows May 4th data.
So … have the US deaths peaked, and if so when? Hard to tell. However, I looked at that graph in Figure 1 and I thought “It looks like the data might be reflecting lower counts on the weekends”.
Now, my go-to method for determining the existence, period, and amplitude of underlying repeating cycles in a dataset is the curious method called “CEEMD”. That stands for Complete Ensemble Empirical Mode Decomposition. I discuss the method here. It is a way to decompose a signal into underlying signals. It’s called “complete” because when you add all the underlying signals back together, it gives you back the original signal.
Once all possible underlying cycles have been removed from the data, what remains is called the “CEEMD Residual”. This residual is an excellent indicator of the overall trend of the data. Here is an overview of the CEEMD decomposition of the daily deaths data shown in Figure 1.

Figure 2. CEEMD complete decomposition of the data shown in Figure 1. The top panel is the raw data. Panels C1 to C4 are the empirical modes. Finally, at the bottom is the CEEMD residual.
As you can see, two of the four empirical modes (C2 and C4) are weak, with very low amplitude. Modes C1 and C3, on the other hand, show a much stronger signal. We can see the periods and strengths of each of the empirical modes C1-C4 in Figure 3, which shows the periodogram of each of the empirical modes C1-C4.

Figure 3. Periodograms of each of the empirical modes shown in Figure 2. The strongest signal is the seven-day signal, showing that my guess about weekends was likely correct. There is also a significant amount of energy in the first overtone of the 7-day signal, with a period of 3.5 days.
So … how does this analysis work out in practice? Here is the same data as in Figure 1, along with the CEEMD residual.

Figure 4. US daily deaths, along with the CEEMD residual. Data from May 4th, analyzed May 6th.
Well, I’d have to say that that looks like good news … it would be excellent if we were indeed 20 days past the peak.
And here is a look with the underlying 7-day signal overlaid on the daily data.

Figure 5. As in Figure 4, but overlaid with the seven-day empirical mode signal (Mode C3). The overlaid empirical mode C3 is shown for illustrative purposes only. You can see that when the empirical mode is added to the residual it will be a good match to the data.
This is a most interesting result. It shows one of the reasons that I use the CEEMD analysis—it breaks the raw data down into meaningful underlying signals. In this case, early in the spread of the virus at the left-hand side of the graph, the 7-day signal (blue line) was quite small. But now that there are a large number of deaths the 7-day signal is much larger. It is this kind of a result that is unobtainable by say standard Fourier analysis.
Finally, I prefer the CEEMD residual method over say a Gaussian smooth because it goes all of the way out to both the start and finish of the data. Not only that, but the information out near the ends is meaningful. Here’s a comparison of the CEEMD residual with a Gaussian filter.

Figure 6. Daily US deaths, CEEMD residual, and 7-day Full-Width to Half Maximum (FWHM) Gaussian smooth of the data. This is data from May 4th, processed on May 6th. Treatment of the Gaussian smooth near the endpoints is discussed in the Appendix here.
As you can see, the Gaussian smooth is high at the start of the daily deaths data, and low at the end of the data. The Gaussian smooth is dropping at the right-hand end, and the CEEMD Residual is turning upwards.
And two days later, here’s the situation:

Figure 7. More recent data, from May 6th, daily deaths and CEEMD Residual
At the right-hand end of the graph, the CEEMD residual was already foreshadowing the turn from decreasing to increasing, at the same time that the Gaussian smoothing was wrongly indicating a further decrease (see Figure 6). As I said, the CEEMD residual contains important information out at the ends.
Conclusions? Well, my first one would be that attempting to analyze coronavirus death data without removing the repeating weekly variations is … well, I’ll call it “overly optimistic” and leave it there.
My next conclusion is that the CEEMD residual is an excellent indicator of the ever-changing and oft-deceptive central tendency in time series data.
Next, about a week ago the CDC changed its guidance on the reporting of deaths involving the COVID virus. Rather than make an explicit distinction between deaths WITH coronavirus and deaths FROM coronavirus, they said to enter COVID-19 on the death certificate if the physician SUSPECTS that the coronavirus MIGHT have CONTRIBUTED to the death … “suspects the virus might have contributed” to the death??? Could they possibly be more vague?
The size of the effect of this change on the way the US reports the death count is unknown, but it can only increase the purported count, not decrease the count. As a result, we cannot be sure that the increase in deaths is real and not just a change in reporting
Finally, it appears that the US has peaked in terms of daily deaths. Might be another peak to come, might be two more peaks, might be no more peaks, but in any case but it appears we’ve passed the first peak.
Stay well, dear friends. When I was a young man, an old geezer (who was likely about my age now) told me “Son, when you have your health you have everything!”
But back then, I didn’t understand …
w.
PLEASE: Quote the exact words you are discussing in your comment. This avoids endless misunderstandings and problems.
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Dear Mr. Eschenbach,
With your data set, is it possible to sort out all deaths of individuals over 70? And examine graphically the daily death rate of only those under 70?
Without being too cold blooded about it and just for statistical purposes, let us assume those over 70 with comorbidities were going to die anyway, covid or no covid.
When did the under 70 daily deaths peak? What does the CEEMD of that time series look like? Just curious…
https://www.washingtonpost.com/health/2020/05/07/blood-thinners-coronavirus-clots/
https://www.medrxiv.org/content/10.1101/2020.03.28.20046144v3
https://onlinelibrary.wiley.com/doi/pdf/10.1002/rth2.12353
I would take low molecular weight heparin for starters (and aspirin probably).
Heparin is safe, anti-inflammatory, prevents blood clotting and inhibits cellular entry of many different viruses.
And if I would be in the risk group or end up in the hospital I would ask my doctor what else can we do without risking bleeding.
https://www.washingtonpost.com/health/2020/05/07/blood-thinners-coronavirus-clots/
https://www.medrxiv.org/content/10.1101/2020.03.28.20046144v3
https://onlinelibrary.wiley.com/doi/pdf/10.1002/rth2.12353
https://annals.org/aim/fullarticle/2765934/autopsy-findings-venous-thromboembolism-patients-covid-19-prospective-cohort-study
I would take low molecular weight heparin for starters (and aspirin probably).
Heparin is safe, anti-inflammatory, prevents blood clotting and inhibits cellular entry of many different viruses.
And if I would be in the risk group or end up in the hospital I would ask my doctor what else can we do to thin my blood without risking excessive bleeding.
I do not trust the “CovID-19” attributed deaths, so I am rather inclined to look at the total deaths. Now a lot of deaths have been averted due to the lock-down (at least in theory), but the total deaths is capturing a lot of CovID-19 deaths that are not counted otherwise. I cannot say for certain that Flu did not cause these extra deaths, but I am a fan of comparing year to year and Flu deaths are likely to follow similar curves.
A CovID-19 death is in the eye of the doctor, but a death is a death and always counted.
There is another possibility…although I kind of hate to share it out loud. Wives may be killing their husbands at an unprecedented rate since they are locked up with them…I know mine is thinking about taking me out! [ 🙂 ]
Robert, keep us informed of how it works out, either way.
“Next, about a week ago the CDC changed its guidance on the reporting of deaths involving the COVID virus. Rather than make an explicit distinction between deaths WITH coronavirus and deaths FROM coronavirus, they said to enter COVID-19 on the death certificate if the physician SUSPECTS that the coronavirus MIGHT have CONTRIBUTED to the death … “suspects the virus might have contributed” to the death??? Could they possibly be more vague?
actual guidance
https://www.cdc.gov/nchs/data/nvss/vsrg/vsrg03-508.pdf
https://emergency.cdc.gov/coca/ppt/2020/04-16-20-transcript.pdf
https://emergency.cdc.gov/coca/calls/2020/callinfo_041620.asp
https://emergency.cdc.gov/coca/ppt/2020/Final_COCA_Call_Slides_04_16_2020.pdf
https://www.cdc.gov/nchs/nvss/covid-19.htm
hmm?
‘”Next, about a week ago the CDC changed its guidance on the reporting of deaths involving the COVID virus. Rather than make an explicit distinction between deaths WITH coronavirus and deaths FROM coronavirus, they said to enter COVID-19 on the death certificate if the physician SUSPECTS that the coronavirus MIGHT have CONTRIBUTED to the death … “suspects the virus might have contributed” to the death??? Could they possibly be more vague?”
hmm citations needed
ya know when people cite “Ar5” and you get pissed because they dont use page numbers?
Sorry, Steven. I’d posted the link to this guidance so many times that I figured even folks like you would have heard about it. My bad, though, should have re-posted the link. Here’s the actual quote from the CDC:
Which is … well … pretty exactly what I’d said from memory. From the CDC here … sorry that you wasted all that snark, maybe you could collect it up and direct it at someone who actually deserves it.
w.
Sorry.
1. Thats march 24th guidance
2. It does not say this
‘‘”Next, about a week ago the CDC changed its guidance on the reporting of deaths involving the COVID virus. Rather than make an explicit distinction between deaths WITH coronavirus and deaths FROM coronavirus, they said to enter COVID-19 on the death certificate if the physician SUSPECTS that the coronavirus MIGHT have CONTRIBUTED to the death … “suspects the virus might have contributed” to the death??? Could they possibly be more vague?”
A) you said a week ago. the document you refer to now is stated March 24th.
B) here is what I found for latest guidance
https://www.cdc.gov/nchs/data/nvss/vsrg/vsrg03-508.pdf, April guidance
C) Maybe you did not go through the latest training materials
D) The codes are U07.2 and , U07.1
U07.2, when there is no test, , U07.1 when there is a test
here is the actual words
“Should “COVID-19” be reported on the death certificate only with a confirmed test?
COVID-19 should be reported on the death certificate for all decedents where the disease caused or is
assumed to have caused or contributed to death. Certifiers should include as much detail as possible based
on their knowledge of the case, medical records, laboratory testing, etc. If the decedent had other chronic
conditions such as COPD or asthma that may have also contributed, these conditions can be reported in Part
II. (See attached Guidance for Certifying COVID-19 Deaths)”
there are 2 codes. One code for when there is a test. One code for when there is no test.
That way you keep them separate and can count on, deaths with tests, deaths with no tests
“Sorry, Steven. I’d posted the link to this guidance so many times that I figured even folks like you would have heard about it.”
it is weird. I remember this kind of argument from the climate wars. With respect to hide the decline. Briffa and CRU arguing that the decline had previously been disclosed in the literature .
Maybe you could clarify further? For example:
“here is the actual words “Should “COVID-19” be reported on the death certificate only with a confirmed test?”
I don’t find those words in the “latest guidance” doc you cited here: https://www.cdc.gov/nchs/data/nvss/vsrg/vsrg03-508.pdf
The actual words in *that* document are (emphasis added):
This appears to blatantly contradict your claim:
“there are 2 codes. One code for when there is a test. One code for when there is no test.
That way you keep them separate and can count on, deaths with tests, deaths with no tests”
How does one “keep them separate and … count on, deaths with tests, deaths with no tests,” when “it is acceptable to report COVID–19 on a death certificate without this [i.e., testing] confirmation if the circumstances are compelling within a reasonable degree of certainty”?
Not that you didn’t find those words you quoted somewhere else in CDC documentation. I’m sure you did.
But which words should we follow?
Those before or those after (depending on which came first and when)?
Who can know?
How can they know?
Where is the final word of wisdom?
Oh dear, “it’s a ‘puzzle'” . . . said a wise man once, somewhere . . .
🙂
Huh? What’s this? Surely not crickets right?
I mean you were JUST here bouncin’ all over W. E. for quoting an old document when your own up-to-date citation says exactly what his old one did?
Sup dood? Come on “techno” bro step up and be the man you want W. E. to be!
“it is weird. I remember this kind of argument from the climate wars. With respect to hide the decline. Briffa and CRU arguing that the decline had previously been disclosed in the literature .”
Yeah, “it is weird,” right? Somebody said: “hmm citations needed,” but when he got ’em he cricketed the field? Surely not the accuser? He wouldn’t do that would he?
🙂
https://www.cdc.gov/nchs/data/nvss/coronavirus/Understanding-COVID-19-Provisional-Death-Counts.pdf
https://www.cdc.gov/nchs/nvss/vsrr/COVID19/
“Why these numbers are different
Provisional death counts may not match counts from other sources, such as media reports or numbers from county health departments. Our counts often track 1–2 weeks behind other data for a number of reasons: Death certificates take time to be completed. There are many steps involved in completing and submitting a death certificate. Waiting for test results can create additional delays. States report at different rates. Currently, 63% of all U.S. deaths are reported within 10 days of the date of death, but there is significant variation among jurisdictions. It takes extra time to code COVID-19 deaths. While 80% of deaths are electronically processed and coded by NCHS within minutes, most deaths from COVID-19 must be coded manually, which takes an average of 7 days. Other reporting systems use different definitions or methods for counting deaths.
Things to know about the data
Provisional counts are not final and are subject to change. Counts from previous weeks are continually revised as additional records are received and processed. Provisional data are not yet complete. Counts will not include all deaths that occurred during a given time period, especially for more recent periods. However, we can estimate how complete our numbers are by looking at the average number of deaths reported in previous years. Death counts should not be compared across jurisdictions. Some jurisdictions report deaths on a daily basis, while others report deaths weekly or monthly. In addition, vital record reporting may also be affected or delayed by COVID-19 related response activities.
For more detailed technical information, visit the Provisional Death Counts for Coronavirus Disease (COVID-19) Technical Notes page.”
warning to all data monkeys
‘Death counts should not be compared across jurisdictions.”
here is a clue. you will not see this data monkey plotting any death data.
and never compare death data across jurisdictions.
When data providers give you fair warning ,you precede at your own risk.
But the nice thing about looking at provisional data is that when you make a mistake
and the data changes under your feet like all provisional data does, you can always blame the supplier.
don’t be bad data monkey.
It is ok to look at the data and start to understand the issues,
but if you publish results based on provisional data,
expect to have the carpet pulled from under your feet.
I’m wondering about classifications of murders by spouses locked in together due to Covid?
Clearly seems caused by Covid.
If you use a death certificate not possible they would die from blunt force trauma, gun shot etc. The problem is the death certificate data can take weeks to get. If you use hospital or media company data maybe, that is up to what data source manager decides.
Depends on coroner, I guess. Two cases:
Twenty-something showed up at UK hospital, had a heart attack, then died. Coroner listed death as covid because he heard she had a cough. Hospital staff disagreed saying she didn’t test positive.
US infant died of drowning and tested positive postmortem. Governor of state publicly declared infant’s death was linked to covid, and was then publicly exposed to be a liar. Coroner refused to register death as covid.
The first case you gave was a massive reporter error the BBC and British newspapers had to offer very public apologies as they cause distress to the family and were looking at damages case.
Mosh,
Just asking.
Are you are you not a techno guy????!!!
I know that not to be the proper question, but never the less.
cheers
Steve, not there!
hello Steve!
cheers
Techno? yes
a week ago the CDC changed its guidance on the reporting of deaths
============
politics as usual. TDS. Changing the accounting method midstream to panic the country and justify their jobs.
I would like to point out that the CDC says hospitals, doctors, and nurses kill 100,000 patients PER YEAR just from preventable hospital infections.
The number of hospital admissions, however, requires no modeling, extrapolation or algorithm. There have been more hospital admissions for flu than for coronavirus.
Laboratory-Confirmed COVID-19-Associated Hospitalizations (Rate per 100,000 population): 40.4
https://gis.cdc.gov/grasp/covidnet/COVID19_3.html
Laboratory-Confirmed Flu Hospitalization (Rate per 100,000, for Nov-May 2019-20 Flu season): 69
https://gis.cdc.gov/GRASP/Fluview/FluHospRates.html
If cv is killing more people, it’s happening in the hospitals.
Figures for England and Wales
from…https://www.ons.gov.uk/peoplepopulationandcommunity/birthsdeathsandmarriages/deaths/datasets/weeklyprovisionalfiguresondeathsregisteredinenglandandwales
All deaths week 17 2019 10,059
5 year average deaths week 17 10,317
All deaths week 17 2020 21,997
and for Scotland from…https://www.nrscotland.gov.uk/statistics-and-data/statistics/statistics-by-theme/vital-events/general-publications/weekly-and-monthly-data-on-births-and-deaths/weekly-data-on-births-and-deaths
All deaths week 14 2019 1032
All deaths week 14 2020 1741
So co-morbidities or not people are being pushed off the branch earlier than previously.
After the virus has passed the death rate may, perhaps, possibly drop as people who were likely to die “soon” have already died.
That won’t be clear until the data are in.
I think this analysis was a nice waste of time. One major problem with looking at deaths by day is that they tend to be *reported* date, not *death* date. For example, there have been several days when a batch of nursing home deaths were added to the NYC statistics, spiking the deaths on those days. But, those deaths happened over a period of time and should be understood to be spread out over multiple days. The weekend spikes could be spikes in *reporting* not *deaths*.
Trivial.
The statistics must week-integrated.
Even this does not help as many report deaths at the end of month.
It’s bureaucracy, not epidemic.
Ann, all your points show why the filtering Willis did was necessary, not why it was a “waste of time”. The
Alex: “statistics must week-integrated.”
No, you do not need to integrate, you can filter. That is Willis did and what I did in by a different means. Both mean you get more than one point per week, and see the trend underlying the weekly variation.
“you do not need to integrate, you can filter”
One can, but one should not do it like Willis did.
The Gaussian average is stable. You cannot apply it at the end of the series of course.
What Willis did, he applied his – whatever – procedure towards the end of the series.
This is a kind of extrapolation, even if it is still within the available data.
Extrapolations are always unstable.
Whatever he got towards the end of the series – a bump or a decay – is meaningless.
“I think this analysis was a nice waste of time. One major problem with looking at deaths by day is that they tend to be *reported* date, not *death* date. ”
yes this has been pointed out many times but guys still continue to plot daily death data.
Now what is worst is that some politicians are also looking at daily death data.
At this stage it is largely pointless to look at time series of death data.
But folks will continue to push agendas by plotting up data before its been through a proper
cleaning analysis.
Again, people did the same thing with early DImand Princess data, same thing with early Korea
death data.
Their is no stopping people from monkeying around with data that hasn’t been properly vetted
Hi Willis, – An old geezer & I were passing the time of day quite a long time ago. We got around to our respective ages after I admired his daily activities. Upon hearing I was in my late 50s he deadpanned: “I got shoes older than you.”
This the second iteration of SARS-CoV…..so far, the first occurrence has not led to the production of an vaccine…and the problems of a vaccine for SARS Version 1 still exist https://www.ncbi.nlm.nih.gov/pmc/articles/PMC525089/
Well, let us watch those, who started earlier.
Europe is by far not the early bird.
Rather, check Iran.
I do not like what I see there.
For a long time, I’ve known and commented about the dip in the death counts on weekends and the subsequent rise on Tuesday. A less obvious aspect of the counts is that just because a death is counted on a certain day doesn’t mean it occurred on that day or the day before. Indiana has one of the best run COVID websites. One of their graphs shows when the newly-counted deaths occurred. In some cases, some of the deaths happened weeks before.
On April 29th I notice a very large jump in the Covid Tracking Project’s U.S. count, and decided to see which states it was coming from. I noticed 164 of the deaths came from Indiana. However, when I looked at the Indiana website, it only showed 63 deaths. When I questioned the Covid Tracking Project, they replied that they were, per CDC guidance, also including suspected deaths. However, the 29th was the first time they included suspected deaths in Indiana’s count; the previous day’s count matched Indiana’s confirmed death count. So all of Indiana’s suspected deaths, which happened throughout the epidemic, were added to the death total in a single day; and 101 deaths in the jump in U.S. deaths on April 29th were attributable to those suspected deaths.
The italian case data has a weekly cycle which is a cycle , not too low days at the weekend. The trough in rate of change peak is Mon-Tues. Due to incubation lag, that probably shows a societal habit from the previous weekend.
One interesting aspect is that the magnitude of the cycle fell by 50% when they reduced restrictions.

I’ll also add that many of the 63 Indiana confirmed deaths reported on April 29th didn’t occur on that day. Currently, Indiana shows 38 deaths on the 29th, and 33 on the 28th. So the report of 164 deaths greatly distorted the actual trend’
I haven’t looked to see if there are similar examples for other states, w]here suspected deaths were added to a total the previously included only confirmed deaths, but I suspect there are.
It appears that the most of European countries that introduced universal BCG vaccination of young children in the 1950s have been spared from the most severe Covid-19 impact.
http://www.vukcevic.co.uk/EuropeCV.htm
Currently only hypothesis, but future research will clear matter one way or the other.
Abstract
“The reasons for a wide variation in severity of coronavirus disease 2019 (COVID-19) across
the affected countries of the world are not known. Two recent studies have suggested a link
between the BCG vaccination policy and the morbidity and mortality due to COVID-19. In
the present study we compared the impact of COVID-19 in terms of case fatality rates (CFR)
between countries with high disease burden and those with BCG revaccination policies
presuming that revaccination practices would have provided added protection to the
population against severe COVID-19. We found a significant difference in the CFR between
the two groups of countries. Our data further supports the view that universal BCG
vaccination has a protective effect on the course of COVID-19 probably preventing
progression to severe disease and death. Clinical trials of BCG vaccine are urgently needed to
establish its beneficial role in COVID-19 as suggested by the epidemiological data, especially
in countries without a universal BCG vaccination policy. ”
https://www.medrxiv.org/content/10.1101/2020.04.07.20053272v1.full.pdf
(p.s. In the ethnically east European compact countries with very little or no ex-european immigration the BCG effect appears to be further reinforced.)
Vuk
According to your effort;
Do actually BCG vaccination or BCG vaccines consist as a stupid beyond stupid flu vaccination?
just asking Vuk!
You tell me please!
BCG is one of the oldest vaccines, if administered at an early age, preferably to preschool children it gives lifetime protection from tuberculosis, one of the better known lung disease. Wikipedia has all about it.
latest update Hegarty et al
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7152883/
“It is ironic that one of our oldest immunotherapies might help against the newest threat facing civilization.”
(one link at the time)
My advice: vaccinate medical staff with a proven and safe tuberculosis vaccine. The autumn and winter wave may be worse than the spring one. Even more so when combined with seasonal flu.
Adults aged 16 to 35 who should have the BCG vaccine
BCG vaccination is recommended for people aged 16 to 35 who are at occupational risk of TB exposure, including:
laboratory staff who are in contact with blood, urine and tissue samples
veterinary staff and other animal workers, such as abattoir workers, who work with animals that are susceptible to TB, such as cattle or monkeys
prison staff who work directly with prisoners
staff of hostels for homeless people
staff who work in facilities for refugees and asylum seekers
healthcare workers with an increased risk of exposure to TB
https://www.nhs.uk/conditions/vaccinations/when-is-bcg-tb-vaccine-needed/
Easy to test: take blood samples from vaccinated vs non-vaccinated, run T cell, B cell and neutralizing experiments.
If you don’t find any mechanism it is just a correlation like storks and babies.
Ireland clearly argues against the BCG hypothesis. One of the worse countries by infected/M (4,533) and deaths/M (284) in Europe.
The Republic of Ireland population is just under 5 million
The largest immigrant groups, with over 10,000 people, are the British, Croats, Poles, Americans, Lithuanians, Latvians, Germans, Nigerians, Indians, Pakistanis and Chinese.
Also there has been large exchange between North and South in the last two decades since the GF treaty. Ireland is far more ethnically diversed than the East European countries.
Both tuberculosis and Covid are lungs diseases, so it shouldn’t be a huge surprise that BCG reduces effects of the Covid lungs infection.
Explanation looks plausible and the medical science needs to find answers urgently, one way or the other.
“The largest immigrant groups, with over 10,000 people, are the British, Croats, Poles, Americans, Lithuanians, Latvians, Germans, Nigerians, Indians, Pakistanis and Chinese.”
Most of those countries have BCG vaccination programs still active. No big impact to be expected. Immigrants might also be vaccinated. That is what health care systems do.
“Both tuberculosis and Covid are lungs diseases, so it shouldn’t be a huge surprise that BCG reduces effects of the Covid lungs infection.”
The misconception COVID-19 to be a lung disease might have killed a lot of people on ventilators. It is not at all primarily a lung disease.
Different mechanisms can lead to the same symptoms. Just looking at symptoms might put you on the wrong track. The evidence is accumulating that this has happened with COVID-19.
BCG efficacy depends on the genetic variation in populations.
“Trials conducted in the UK have consistently shown a protective effect of 60 to 80%, but those conducted elsewhere have shown no protective effect, and efficacy appears to fall the closer one gets to the equator.
….. Native Americans immunized in the 1930s found evidence of protection even 60 years after immunization, with only a slight waning in efficacy.” -wikipedia
It looks that the Covid-19 may have some genetic factors attached to intensity of infection and consequently mortality.
Out of season flu or devious killer, the Covid-19 science is far from being settled. It would be good to know.
Vuk, the UK had universal BCG vaccination from the 50s until 2005 as I recall. I remember we were tested/vaccinated at high school. It’s hard to believe that the UK has been spared.
BCG vaccination apparently is most effective it administered at a very young age, however the high school age vaccination may lose effectiveness some 15 to 20 years later, it could be something to do with the body mass at the time of the vaccination. I am told that was vaccinated at age of four.
Apparently differences in genetic make-up of different populations may explain the difference in efficacy, some studies carried in India show low vaccine’s efficacy in the indigenous population.
Currently in the UK there are reports that people of Asian and African genetic make up have four times mortality to that of the indigenous British (apparently mostly those of the high age, those with serious underlining medical issues and the overweight not to say obese).
Boris Johnson may have or have not been vaccinated as a young child it has mixed Turkish/white European ethnicity and was rather overweight, while dozen of his parliamentary colleagues including two or three ministers were infected at more or less same time but none (as far as I know) needed hospitalisation.
That’s not what the paper you cited said Vuk. It referred specifically to revaccination policies not vaccination of young children. Also one of the countries supposedly benefiting from this practice is Russia, the table cites Russia as having 1534 cases and 8 deaths, latest data is 187,859 cases and 1,723 deaths!
Revaccination is adults not very effective against tb and it is unlikely to be much effective against Covid-19. Only difference between west and east European countries is that east is genetically more compact and all adults were BCG vaccinated as small children. CV arrived there late and they are already lifting lockdowns.
Hopefully science might be able to find out reasons for the large disparity in death rate.
Vuk May 9, 2020 at 12:45 am
Revaccination is adults not very effective against tb and it is unlikely to be much effective against Covid-19.
But that’s exactly what the paper you quoted is about.
Only difference between west and east European countries is that east is genetically more compact and all adults were BCG vaccinated as small children.
But the difference that was cited in that paper was whether they revaccinated or not.
Willis:
Like you, I am a data junkie and want to attempt to repeat the analysis on the UK dataset because it also shows a strong 7-day periodicity. Unfortunately, the link to the code that you provide in your December 2015 post: https://dl.dropboxusercontent.com/u/96723180/Amazon%20Flow.R now shows Error 404.
Can you assist?
Willis, I’ve always been suspicious of the technically invalid extensions of spreading convolution or iterative filters out to the end of data, though I’ve never wanted to spend the time to find a case where it does not work. You have just provided such an example.
The gaussian filter removes all visible trace of the cycle up to the last week where you need to start padding and recycling. There we see that there is a fair amount of the weekly variability which makes it through the filter, though it is strongly attenuated. This clearly leaves a misleading visual impression as to where the underlying trend is going.
Anyone who thinks CV19 is just a bad seasonal flu that selectively kills oldies with existing health issues should take a look at the 26 pages here:
https://www.medscape.com/viewarticle/927976?src=wnl_tp10n_200508_mscpedit&uac=362613SR&impID=2373561&faf=1#vp_26
Clearly from the comments it is incomplete. Also, it is less than 4 months since the first.
“CV19 is just a bad seasonal flu that selectively kills oldies with existing health issues”
Well, yes, it does. The list shows it clearly.
This virus will limit our life expectancy.
The medics are exposed to huge viral loads and one has to deconvolute the age of the medics and the probability to die.
Same old, same old-
1957 flu killed over 1 million of all ages. These things happen .
The weekly cycle appears to me an artifact of the reporting process, bunching counts near particular days of the week. Otherwise one has to explain a little conundrum: how does the virus know it is Sunday?
Just working hours pattern statistic in the testing labs, hospital emergency units staffing and ‘working from home’ of the data compilers. “Friday afternoon car” syndrome.
The weekend effect has been noted by many.
FFS Cuomo talks about it constantly.
basically you should be looking at 3 day or 7 day averages
I would like to know how data on deaths is parsed and resolved due to the decision by many hospitals and facilities to include the death of the patient by the presence of the Covid virus regardless of the actual cause of death. A statistical nightmare of resolution.
Jeff Smathers,
I’ve been asking the same questions. I’ve come to find out that a counted COVID-19 death is an opinion. Some further questions are: does a positive COVID-19 death mean no other tests were administered or that a whole range of other tests were administered and they all came back negative? Or just some other tests? What other viruses were present? Does anyone know?
Andrew
I suspect that a large part of the weekly cycle is simply a failure to report deaths until the next working day.
comes down to one thing , are the numbers correct.
Withe youtube and Google removing any voices of skepticism we can see that the numbers are not to be believed. It has become political.
Illinois counts all deaths “with” Corona as death “from” corona. “All” not just suspected. It’s not vague in the least. It is over counting. This method is in widespread use across the USA.
The death counts are NOT to be trusted. I think the best way to measure the increase or decrease of the virus is Covid admissions to hospitals. But try to find that by state on a daily basis. Good luck.
Taylor Swift – Blank Space
cheers