More good news about the Chinese virus, and the Easter Funny

By Christopher Monckton of Brenchley

The good news keeps coming. In the United States and Canada, the weekly-averaged daily compound growth rates of confirmed cases of infection are now about 8%, down from the benchmark values of 23% and 17% respectively that obtained in the three weeks to March 14, when Mr Trump declared the pandemic to be a national emergency.

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Fig. 1. Mean compound daily growth rates in confirmed cases of COVID-19 infection for the world excluding China (red) and for several individual nations averaged over the successive seven-day periods ending on all dates from March 28 to April 11, 2020. A link to the high-definition PowerPoint slides is at the end of this posting.

The daily case-growth rate for the world excluding China and occupied Tibet is down from the benchmark value of almost 20% in the three weeks to 14 March to just 6.1% for the week to 11 April.

The daily compound rate of growth in deaths is a lagging indicator, so it remains rather higher than the case-growth rate. For the world outside China and occupied Tibet, it is 8.1%. In the United States it is 13%, in Canada 16%. Though the overall trend in these death-growth rates is falling slowly, there will be many more deaths before the pandemic subsides.

Daily growth rates in deaths are falling rather more slowly on average than growth rates in total confirmed cases, but the overall trend is downward.

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Fig. 2. Mean compound daily growth rates in reported COVID-19 deaths for the world excluding China (red) and for several individual nations averaged over the successive seven-day periods ending on all dates from April 4 to April 11, 2020.

The Spectator reports that in the town of Gangelt, one of the epicenters of the German outbreak, a random sample of 1000 residents taken by researchers at the University of Bonn found that, though only 2% of the sample showed symptoms, 15% had been infected and showed antibodies. Yet the confirmed cases reported by Germany as a whole to April 11 were just 125,452, or 0.15% of the population of 84 million.

In short, the confirmed cases, which tend to be the more serious ones, appear to undercount the true extent of infection by two orders of magnitude. This came as a surprise to many, but to those who have been following these daily updates it will have been no surprise, because, based on casting back deaths three weeks, I was able to discover that the number of cases of infection was being under-reported by somewhere between 1 and 3 orders of magnitude.

This is good news for two reasons. First, we are much further along the road to population-wide immunity than the confirmed-case counts had suggested. Secondly, the case fatality rate appears to be a great deal smaller than the ratio of deaths to reported cases had indicated. My original rough-and-ready calculations based on casting back deaths in the U.S. population suggested a case fatality rate of 0.34%. The German researchers concluded that it was 0.37%.

In global terms, these figures suggest that, assuming 90%, or 7 billion, of the world’s 7.8 billion population eventually became infected, total worldwide deaths would be about 26 million, making the disease about half as bad as the Spanish flu of 1918-19, which chiefly killed young people and accounted for an estimated 50 million deaths. In the United States there would be 1.1 million deaths. For comparison, in the 2019-20 flu season there are thought to have been 24,000 to 62,000 deaths, according to the Centers for Disease Control.

So the fatalities could still be significant, based on the German study. However, several promising avenues of research into prophylactics, palliatives and cures are being followed worldwide. The sooner some of these are shown to have a significant effect in randomized, prospective, double-blind, placebo-controlled clinical trials, the smaller the eventual death toll will be.

A happy Easter to everyone. And, by way of an Easter Funny, here is a picture of the personal protective equipment that the fashionable Peer of the Realm is wearing this season.

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Original slides here.

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ren
April 13, 2020 4:25 am

Prime Minister Boris Johnson has said it “could have gone either way” as he thanked healthcare workers for saving his life after being discharged from hospital.

Mr Johnson, 55, was taken to London’s St Thomas’ Hospital on Sunday – 10 days after testing positive for Covid-19.

He spent three nights in intensive care before returning to a ward on Thursday.

He said in a video on Twitter that he had witnessed the “personal courage” of hospital staff on the front line.

Mr Johnson said two nurses – Jenny from New Zealand and Luis from Portugal – stood by his bedside for 48 hours at the most critical time and named several other hospital workers who cared for him this past week that he wanted to thank.

He said NHS workers “kept putting themselves in harm’s way, kept risking this deadly virus”.
https://www.bbc.com/news/uk-politics-52262012

Fabio Capezzuoli
April 13, 2020 6:53 am

Sir Monckton, I would ask if you could kindly provide the data for Italy and Sweden in tabular form for my personal research.
Due credit will of course be given.

ren
April 13, 2020 7:32 am

ABSTRACT
The beginning of 2020 brought us information about the novel coronavirus emerging in China. Rapid research resulted in the characterization of the pathogen, which appeared to be a member of the SARS-like cluster, commonly seen in bats. Despite the global and local efforts, the virus escaped the healthcare measures and rapidly spread in China and later globally, officially causing a pandemic and global crisis in March 2020. At present, different scenarios are being written to contain the virus, but the development of novel anticoronavirals for all highly pathogenic coronaviruses remains the major challenge. Here, we describe the antiviral activity of previously developed by us HTCC compound (N-(2-hydroxypropyl)-3-trimethylammonium chitosan chloride), which may be used as potential inhibitor of currently circulating highly pathogenic coronaviruses – SARS-CoV-2 and MERS-CoV.
https://www.biorxiv.org/content/10.1101/2020.03.29.014183v1?fbclid=IwAR12q0EkY2tyBv1WY5TWn5Trh92WJhCEvriR1e3ku1Qn4VeGLN08aXF-6VE

John Tillman
Reply to  ren
April 13, 2020 9:07 am

Great if the Polish-Chinese polymeric inhibitor works!

John Tillman
April 13, 2020 7:36 am

Trend on the mend?

Daily deaths in the US attributed to COVID-19:

07 April 1973
08 April 1943
09 April 1901
10 April 2035
11 April 1830
12 April 1528

As deaths are a lagging indicator, the decline may foretell return to freedom sooner.

Tom Abbott
April 13, 2020 8:45 am

From the article: “In the United States there would be 1.1 million deaths.”

The official estimate which began this U.S. shutdown was for the number of deaths to be between one million and 2.2 million, if nothing is done to modify the spread of the virus, and with social distancing, the numbers could be lowered to 100,000 to 240,000 deaths, based on 50 percent of Americans following the social distancing rules.

So Mr. Monckton’s estimate of 1.1 million is pretty close to the initial estimate’s low end.

Michael Carter
April 13, 2020 10:46 am

“What bike do you ride, out of interest? I picture you on a vintage BMW boxer, or on the more patriotic side, a Triumph Thruxton.”

I am sure that it won’t be a Harley Ferguson

RobR
Reply to  Michael Carter
April 13, 2020 11:57 am

Ducati…..scroll up

John Tillman
Reply to  Michael Carter
April 13, 2020 12:36 pm

Or a Massey Davidson!

John Tillman
Reply to  Michael Carter
April 13, 2020 12:39 pm

Or a Massey Davidson!

(Apologies if this is a repeat.)

richard
April 13, 2020 11:55 am

Real problems with results-

“A study in the Journal of Medical Virology concludes that the internationally used coronavirus test is unreliable: In addition to the already known problem of false positive results, there is also a „potentially high“ rate of false negative results, i.e. the test does not respond even in symptomatic individuals, while in other patients it does respond once and then again not. This makes it more difficult to exclude other flu-like illnesses’

https://www.ncbi.nlm.nih.gov/pubmed/32219885

chm
April 13, 2020 3:16 pm
Stevek
April 14, 2020 3:39 pm

I have read that the bat virus closest to this comes from bats that live in caves 1000 miles from Wuhan. I have read the biological lab in Wuhan had technicians collect samples from those caves.

So how did this virus from 1000 miles away get to Wuhan ? It could have infected an animal and the live animal shipped to Wuhan. But I believe equally probable or even more probable the virus got to Wuhan from samples collected.