Backstory: Origins of the COVID-19 Virus

Guest post by Dave Archibald

Who does the virus call ‘Daddy’? In the 1950s, oil geologist Michel Halbouty said that “oil is first found in the minds of men“, meaning that someone has to imagine the existence of an oil field before they can go out to find it. The same is true of most of the fruits of mental endeavour.

Similarly, the COVID-19 virus is artificial so someone conceived it in his mind before it was created in the lab.

The construction of the place where the virus was created, the Wuhan Institute of Virology, was funded by the French government in 2004 in an attempt to ingratiate themselves with the Chinese dictatorship. Upon completion, the Chinese let only one Frenchman into the building.

3D Architectural rendering from http://english.whiov.cas.cn/About_Us2016/Brief_Introduction2016/

The events that led to the making of the virus started decades before with the founding of The Wildlife Trust in 1971 by English wildlife lover Gerald Durrell. Its headquarters moved to New York. In 1997 the Wildlife Trust spun out The Consortium for Conservation Medicine. This organisation has been described as a “unique collaborative institution that strives to understand the link between anthropogenic environmental change, the health of all species, and the conservation of biodiversity.”

In other words, it is a spiritual home for health academics worried about global warming.

The Wildlife Trust and the Consortium for Conservation Medicine merged in 2010 to form the EcoHealth Alliance. One benefit from the name change would have been to enable government health bodies to give it money.

Dr Anthony Fauci and his offsider at the National Institutes of Health, David Morens, have been publishing papers like this one since 2004.  In that paper they list ‘Intent to harm’ as a contributing factor in the emergence of infectious diseases.  This is expanded in a paragraph on ‘Deliberately emerging infections’:

Deliberately emerging microbes are those that have been developed by man, usually for nefarious use. The term ‘deliberately emerging’ refers to both naturally occurring microbial agents such as anthrax 6 , and to bioengineered microorganisms such as those created by the insertion of genetic virulence factors that produce or exacerbate disease. Deliberately emerging microbes include microorganisms or toxins produced in a form that would cause maximal harm because of ease of dissemination, enhanced infectivity or heightened pathogenicity.

The first of Fauci and Morens’ subsequent papers to mention “global warming in the emergence of diseases” was this one from 2008. About the same time, virus researchers in the US started doing interesting things. Two labs altered the H5N1 avian flu strain so that it was more readily transmittable between ferrets. Ferrets use the same cellular receptors as humans for the virus, and strains that infect people spread among ferrets and cause similar symptoms. This is ‘gain of function’ research which is another way of saying they were trying to make deadly viruses yet more deadly. Because of lab mishaps, gain of function research was outlawed in the US in 2012.

It was at this time that somebody, one Nicholas Evans, nailed Fauci’s idee fixe. In a reply to a paper co-authored by Fauci’s sidekick Morens is this sentence:

To claim that nature conducts research is playing fast and loose with the criteria; that nature breaks the rules smacks of an animism that is hard to fathom.

Fauci has got animism, the attribution of a soul to plants, inanimate objects, and natural phenomena, really bad.

Fauci reacted to the ban on gain of function research by taking it to China. This was channelled through his ideological soulmates at EcoHealth Alliance. As Rudi Giuliani said in an interview:

Back in 2014, the Obama administration prohibited the U.S. from giving money to any laboratory, including in the U.S., that was fooling around with these viruses. Prohibited. Despite that, Dr. Fauci gave $3.7 million to the Wuhan laboratory. And then even after the State Department issued reports about how unsafe that laboratory was, and how suspicious they were in the way they were developing a virus that could be transmitted to humans, we never pulled that money.

This is why the US consulate in Wuhan visited the lab a number of times and wrote reports complaining about the poor biosecurity standards there. A lab mishap duly occurred at the Wuhan Institute of Virology. Satellite imagery shows road blocks around the lab on 6th to 11 October, 2019. This is supported by US mapping of mobile phone traffic which showed a reduction in traffic from the affected building. The Russians realised that troop movements could be mapped by the US from mobile phone data so Putin banned Russian troops from carrying mobile phones a week later.

The virus spread. Zinc is known to inhibit viral replication. Doctors in Wuhan remembered a 2014 paper which showed that chloroquine is a zinc ionophore and found that it worked in treating infected patients. On 22nd May, 2020. medical journal The Lancet joyously published a paper stating that chloroquine doesn’t work. Medical authorities around the world reacted by withdrawing chloroquine from treatment of the Wuhan virus. Death rates spiked up dramatically about two weeks later. This is illustrated by the experience in Switzerland, as shown by the following graphic from France Soir:

The grey-shaded area is the period of increased deaths in Switzerland due to the study in The Lancet. The death rate jumped 13 days after the administration of chloroquine was withdrawn, it dropped 13 days after the resumption of dispensing chloroquine. That was just Switzerland. The Lancet retracted the paper on June 4th, more over the damage it was doing to its reputation than embarrassment at the number of deaths it caused. Nobody in the media has displayed any interest in who was behind this hit job on chloroquine.

It has been estimated that the media blitz against chloroquine resulted in 80,000 deaths around the world.

A similar hit job was attempted on the diabetic drug metformin which had also been found to be effective against the Wuhan virus.  From down in the comments it is noted that “hydroxychloroquine did show excellent results just for prophylaxis of diabetes” in a paper from April, 2019. So it seems that diabetic drugs are effective against the Wuhan virus, perhaps all of them. This is due to reduced conversion of sugars to fat. Chloroquine combines that effect with being a zinc ionophore.

Somebody funded the hit jobs on chloroquine and metformin but there has been no interest in finding out what motivated these. The lesson from this is that medical researchers are quite happy to cause the deaths of tens of thousands, if you cross their palms with silver. So you can imagine how readily climate scientists can keep up their fraud – nobody dies straight away and they may not be proved wrong for decades.

Now back to Dr Fauci. In September he and his sidekick Morens published the latest iteration of their 2004 paper. Fauci’s weltanschauung is succinctly put in this paragraph from the September, 2020 paper:

The COVID-19 pandemic is yet another reminder, added to the rapidly growing archive of historical reminders, that in a human-dominated world, in which our human activities represent aggressive, damaging, and unbalanced interactions with nature, we will increasingly provoke new disease emergences. We remain at risk for the foreseeable future. COVID-19 is among the most vivid wake-up calls in over a century. It should force us to begin to think in earnest and collectively about living in more thoughtful and creative harmony with nature.

What does that remind us of? It reminds us of the Unabomber’s manifesto which stated in part that modernity has,

“…subjected human beings to indignities, has led to widespread psychological suffering (in the Third World to physical suffering as well) and has inflicted severe damage on the natural world.”

Fauci’s writing style is better than the Unabomber’s but otherwise there is no difference. But now we have motivation. Why would Fauci send all that money to the Wuhan lab knowing that they would use it to manipulate bat viruses to make them infectious in humans?

He is a global warmer and the warmers have a big problem. The world has failed to heat up as predicted, instead remaining stubbornly pleasant. The appearance of the Wuhan virus suggests (at least to those who beleiev such things) that Nature is taking its revenge on humans for not living in harmony with it. Dr Fauci, with the means and the motivation, just gave it a little help along.

President Trump has said that China should be made to pay for the Wuhan virus. Not so fast. It is possible that a bit of investigation may find that the origin was just down the road at 9000 Rockville Pike, Bethesda, Maryland, where Dr. Fauci works.

It has been said that global warming has yet to kill anybody.  In all likelihood that remains true but belief in global warming has now killed over a million people.

If you think that is a bit far-fetched, consider that Voltaire predicted just such an eventuality when he said ‘Those who can make you believe absurdities, can make you commit atrocities.’ Global warming is the biggest absurdity of the modern era – it can’t happen in theory and hasn’t happened in practice. A big absurdity begets a proportionate atrocity.

David Archibald is the author of American Gripen: The Solution to the F-35 Nightmare

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fretslider
October 17, 2020 5:43 am

Cracks are beginning to appear. The English North South divide

Could Burnham win the battle of the North? Boris backed down from forcing Manchester into Tier 3 ‘because he feared police would not enforce rules’ – and figures show the city’s infections are still going DOWN

Greater Manchester Police currently answers to the city’s Labour Mayor, while police and crime commissioners – a role filled in Manchester by Mr Burnham – have the power to set strategic priorities for their local constabularies.

This means that police enforcement of restrictions is contingent on the support of Mr Burnham, who is refusing to move the region into Tier Three without a full reinstatement of the furlough scheme.
https://www.dailymail.co.uk/news/article-8850005/Boris-Johnson-backed-imposing-Tier-3-Covid-rules-Manchester-amid-policing-fears.html

I think we should sue the US and Dr Fauci….

John Tillman
Reply to  fretslider
October 17, 2020 6:32 pm

Sue Neil Ferguson, perpetrator of the bogus Imperial College London model used to justify shutting down Western economies, and relied upon by Democrat governors to send infectious patients into nursing homes.

They did the opposite of what was required, ie they sent old, sick people into enclosed spaces with the most vulnerable, while quarantining the young and healthy. Instead, isolation wards for the infected were what a real doctor would have ordered.

October 17, 2020 6:49 am

I wonder how I could trust this author.
He wrote in his column of January 2020 about 300 Kg of weapon grade plutonium Japan returned to the US this way;
“That is why Japan developed its own nuclear reprocessing industry which could be used for a weapons-based program. As a result of that reprocessing, which runs at a loss, Japan has accumulated 47 tons of reactor-grade plutonium. This is useless for making weapons because its Pu240 content is too high at about 20%. Weapons-grade plutonium has a Pu240 content of 7% or less. Japan did have 300 kg of weapons-grade plutonium the United States had lent them in the 1960s. That would have been enough for 50 fifty-kiloton weapons (assuming that they were tritium-boosted). China was agitated by this and so the Obama regime insisted on its return in 2014. One cheap way of helping keep the peace in Asia would be to send those 300 kg back to Japan.”
「Occasional Cortex: Therefore Japan Goes Nuclear」(January 31, 2019 By David Archibald)
https://www.americanthinker.com/articles/2019/01/occasional_cortex_therefore_japan_goes_nuclear.html

He is right about Obama’s request date of early 2014 but it was March 2016 when 300 Kg arrived at the final destination, Savannah River Site, two full years after the pledge of Abe, then prime minister of Japan.
The US lent Japan 300 Kg for research purpose more than 50 years ago and it was used for making MOX fuel mixing with uranium for fast-breeder reactor experiment.
As Japan did not return in the form of MOX fuel and you cannot recover 239Pu fully from MOX fuel, how could Japan return 300 Kg intact? This is the question of commonsense.
I have a theory on 300 Kg and Fukushima cover up and I want to discuss this issue with the author before taking his Wuhan theory as it is.

David Archibald
Reply to  Hideo Watanabe
October 17, 2020 6:46 pm

Fukushima was a bad reactor design and bad placement. We don’t have a great deal of time to get ready for China’s war. When the Chicoms start losing they are likely to start nuking Japanese cities, one at a time, until the Japanese tap the mat. It is time for the US to lease at least 30 warheads of 400 kt to Japan. So that China’s aggression stays conventional.

Reply to  David Archibald
October 17, 2020 7:11 pm

Whatever the old design of the reactor, the problem was that fuel tanks for backup power for coolant flow were not located high enough to be out of the earthquake’s waves. They were deliberately placed high but the forecast of maximum wave height was not enough. Much has been learned about earthquakes in the over half century since the plant was designed.

Of course extreme events can occur, but on the other hand design to ‘very bad things shall not happen’ is an approach increasingly being used for airliners, replacing traditional <1E-12 type calculations. A problem with calculations is estimates of variables within them, and having to foresee all possible failures is a difficult task. To the extent that the USSR was rigorous, would anyone have included "operators violate procedures in order to test a theory"?

(The mining industry is also shifting away from 'tailings ponds' to slash the downside risk. In one disaster in BC the mine operator was not keeping up with widening the width of the bottom of the dam as it was raised, geoscientists who were supposed to be keeping tabs on things were slow or worse, so a unmapped strata under a wing of the dam liquified under pressure. (For some reason designers had not drilled deep enough to detect it even though they found such strata under the front of the dam. As usual multiple factors combined to make disaster.)

Reply to  David Archibald
October 17, 2020 10:50 pm

Chinese are not that stupid and there is no reason for them to nuke us.
If you are American, you had better make more efforts to reduce the tension in Asia Pacific because there is westerlies toward American continent.
EPA detected massive 239Pu plume in California 9 days after the explosion of SFP of Fukushima Unit 4 on March 15, 2011and a large amount of unusual 234U was also monitored in Alaska. Fresh depleted uranium from enriching reprocessed uranium has 236U, naturally non-existent isotope, in it and more 234U.
Thanks to the wind direction, IAEA laboratory located 100 Km down south from Fukushima monitored 236U. Researchers there could not understand why because there were no fuels which contain 236U in Fukushima officially.

The formula to make MOX fuel to use weapon grade plutonium mixing with fresh depleted uranium was agreed in 2010 between US and Russia for the reduction of excessive amount of weapon grade plutonium.
Unit 4 was not in operation when the accident happened and GE-Hitachi, not Tepco, was working some repair work exclusively and what they were doing has never been disclosed.
I have quite a few copies of FOIA documents that show how badly Obama administration wanted to hide the fuel damage of SFP of Unit 4.

Let me talk briefly how Unit 4 was covered up.
It was April 2, 2013 when the final report on Fukushima was published by UNSCEAR which said that reactor core of Unit 1 to 3 were severely damaged but it is considered that there was no radioactive release from the SFPs at Units 1-4.
However, in the IAEA Technical Volume 1/5 published August 2015 there are daily records and March 15 states;
“At 09:38, a fire reported on the north-west part of the Unit 4RB. It was observed later this fire had self-extinguished at 11:00.
The ERC recovery team tried to enter the RB at 10:30 in order to confirm the state of the SFP regarding to a reported fire, but abandoned the attempt because the dosimeter displayed a maximum rate of 1000 mSv/h upon opening the RB door.

The maximum radiation dose rate of Fukushima accident is manipulated to be 12mSv/h, which was recorded at the main gate at 09:00 on the same day. Nobody knows the exact dose rate because 1000 mSv was the measuring limit of the equipment. There is a conspiracy, not conspiracy theory, in this world.
Why this author does not mention strange pneumonia cases occurred in the US in 2019 which is said to have causality with vaping? This phenomenon seems equally important to find the origin of corona virus.

David Archibald
Reply to  Hideo Watanabe
October 18, 2020 5:27 pm

When China starts its war, either they win or Xi is killed in the subsequent coup. To preclude dying himself, Xi will kill any amount of other people by whatever means available. Japan alone could defeat China in a conventional war. So at some stage Xi (China) will start lashing out in desperation.

Reply to  Hideo Watanabe
October 20, 2020 7:19 am

I think they found out the lung disease caused by vaping was from vape juice with some sort of vitamin E derivative in it. Vitamin E acetate. They also think it was mostly or maybe all people who were vaping stuff with THC in it, Some may not have wanted to admit what they were using.
It was mostly in August and by September was tapering off.
https://www.cdc.gov/tobacco/basic_information/e-cigarettes/severe-lung-disease.html#what-we-know

Reply to  Nicholas McGinley
October 20, 2020 6:23 pm

I know what CDC said. I don’t take it as it is. Despite the average age of patients is 51 years old, Trump raised age limit from 18 to 21. Strange, isn’t it?

Reply to  Nicholas McGinley
October 22, 2020 3:13 am

Does not seem strange to me.
Sentiment in the US is that smoking is a bad thing to do, and the companies have been long known to market their products to younger people.
A few decades ago, many states raised the legal age to buy alcohol from 18 to 21.

As for the CDC, it is not just them saying it.
There are no new reports of people winding up in hospitals with mysterious and rare lung damage.
But we are all free to think anyone and everyone is lying about everything.
Then what?
Just make up our own facts?
You have not said why you think there is any link to COVID.
The cause of the injury was found.
What reason to doubt the findings?

Kevin kilty
October 17, 2020 7:25 am

Despite all the wrangling and misinformation in this thread, I learned something here — I was introduced to Michel Halbouty! Knew nothing of the man before.

From Wikipedia:

Halbouty was fond of citing Wallace Pratt’s dictum that “Oil is found in the minds of men”, to encourage more creativity in oil exploration. Halbouty died at age 95, while working on a West Texas oil project.

So, the quote was not his, but still what a remarkable man. Obviously it took death to put an end to his projects. Bankrupt twice and came back both times. Found 30 oil fields.

Teddylee
October 17, 2020 8:19 am

Uyghurs,Tibet,Hong Kong, Repubic of China,Territorial claims ,wholesale corruption in Western Countries ,correction treatment any dissent and failing to inform the world of the impending disaster,that was COVID-19. Apologists comments expected.

siamiam
October 17, 2020 10:37 am

nerdhaspower.weebly.com has something to say both scientific and forensic about COVID19 and RaTG13.

newt2u
October 17, 2020 11:15 am

I thought this blog was about science. On the origins of the virus, this piece is just speculation, no evidence just a bit of circumstantial evidence that we have to take on trust anyway as there is no link to any source material.

Disappointed!

Steven Mosher
Reply to  newt2u
October 18, 2020 4:56 am

yes look it is impertative for Covid skeptics to fill the air with dust and confusion.
any story will do no matter how far fetched.

They can’t believe their lives have changed forever, and they had no control over it

David Archibald
Reply to  newt2u
October 18, 2020 5:30 pm

Well displace my stuff with better stuff from your own hand. Explain why Fauci sent that money to Wuhan.

Steven Mosher
Reply to  David Archibald
October 18, 2020 8:12 pm

sending money to wuhan is not proof of the biological origin of a virus.
it’s not even evidence.

You dont even know how much money was sent to wuhan or what they did.
( travel and collect samples)

as for the funding. the 3.7 Million was Not directly to Wuhan, it went to ecohealth

In 2014, the NIH approved a grant to EcoHealth Alliance designated for research into “Understanding the Risk of Bat Coronavirus Emergence.” This involved collaborating with researchers at the Wuhan Institute of Virology to study coronaviruses in bats and the risk of potential transfer to humans. Other agencies and researchers NOT IN WUHAN also recieved
portions of this 3.7M

The project wanted to understand what factors allow coronaviruses, including close relatives to SARS, to evolve and transfer into the human population

Over the entire history the Wuhan Institute received about $600,000 from the NIH. the money was a fee for gathering and analysing of bat samples.

the research was not for gain of function

In 2014 ~$133,000 was sent to the institute in the first four years ~ $66,000 coming in the last year. For In 2019 ~$76,000 was budgeted for the Wuhan Institute no money was actually sent.

Here is the top level link, if you contact ecohealth, they can verify the small sums sent to wuhan
and details I provide for you above

https://taggs.hhs.gov/Detail/AwardDetail?arg_AwardNum=R01AI110964&arg_ProgOfficeCode=104

John Tillman
Reply to  David Archibald
October 19, 2020 10:05 am

I don’t think that FauXi intended to kill people. IMO, he, obviously like others at NIH and CDC, contrary to non-governmental epidemiologists and virologists, actually thought there was some value in patently dangerous GoF research.

October 17, 2020 4:21 pm

Alert!

Opinions vary, one research paper concludes the virus was not created in a lab, given detail characteristics.

Researchers in Communist China have worked with bats, which are a reservoir of some diseases, apparently they are not much affected by corona virus.

Thus it is conceivable that sloppy lab workers or deficient facilities.

One _theory_ is that some miners caught the virus and were in a hospital for months with a then unknown illness.

Speculators seem to miss that COVID-10 resembles INFLUENZA thus may well have been misdiagnosed initially. Analysis of sewage samples in Italy suggests the SARS-CoV-2 virus was about several weeks or more before it was recognized there.

(Apparently there is much travel between Communist China and northern Italy for manufacturing to get Made In Italy label. Similarly, it popped up in Iran which has Communist Chinese supplying missiles for proxies to shoot at Israelis, and providing training. There is significant travel between Iran and Canada due immigration and students, many ex-pats ad students went to Iran over the Christmas break, that was a path into North America. (There were direct paths too, notably into Vancouver BC which has many emigres from CC and HK.)

John Tillman
Reply to  Keith Sketchley
October 17, 2020 5:06 pm

Do you refer to the paper which concluded on dubious grounds, that the WuWHOFlu virus was not genetically engineered? In a strict sense, that’s probably correct, where “genetic engineering” means inserting new sequences into existing genomes.

However, SARS-2 was created by a different technique, ie gain of function via directed evolution. Hence, it appears as is it evolved naturally, rather than in a lab, using ferrets as models for human lungs.

Despite my use of “flu|, coronaviruses are quite distinct from influenza viruses. While symptoms in infeccted patients overlap, the two viral families are separated by untold generations of divergent evolution.

CoVs are closer to the ancestral Ur-RNA virus, which was an enveloped, positive-sense, single-stranded replicant. They constitute Family Coronaviridae in Order Nidovirales, Class Pisoniviricetes, Phylum Pisuviricota, Kingdom Orthornavirae, Realm Riboviria.

Influenza A viruses are multi-strain species and genus of enveloped, negative-sense, segmented, single-stranded members of Family Orthomyxoviridae, Order Articulavirales, Class Insthoviricetes, Phylum Negarnaviricota, Kingdom Orthornavirae, Realm Riboviria. So same realm and kingdom, different phyla. As distinct as chordates from arthropods in Kingdom Animalia. As its name implies, Negarnaviricota contains negative-sense viruses.

Reply to  John Tillman
October 17, 2020 5:46 pm

I think he means to say that the disease, not the virus, shares many symptoms and initial disease progression with other respiratory infections.
They mostly all do at some stages, because the symptoms are caused by our immune response, not anything specific to the viral genome.
For example, a very long list of infectious organisms cause pneumonia.
Viruses, fungi, bacteria…many types and strains of each all cause the same sort of symptoms at various stages.
Even doctors that see patients every day have to do a swab and culture to know if someone has an actual case of influenza.
Over 200 different viruses all cause the common cold.
Rhinoviruses, coronas, adenoviruses, and some others.

John Tillman
Reply to  Nicholas McGinley
October 17, 2020 6:14 pm

WuWHOFlu also has symptoms not shared by flu strains. This isn’t an exhaustive list:

https://www.mayoclinic.org/diseases-conditions/coronavirus/expert-answers/coronavirus-unusual-symptoms/faq-20487367

BTW, my wife, a Chilean nurse fighting COVID-19 in Santiago, has been separated from her family, son and me in Valparaiso for seven months, under preventative quarantine since even before Chile entered its state of emergency in April. Valpo came out of total quarantine on Tuesday, entering the still strict Phase 2.

Reply to  John Tillman
October 17, 2020 6:35 pm

Of course.
In many ways it is nothing like any other virus we have seen.
Which become apparent over time, and may even be obvious once everyone is looking very closely for the difference and there is a pandemic.
It was obvious after some time, but how obvious when no one is looking and it is the first few days or a week?
I have read reports from ER doctors about the very early days, when no testing was available, and even when it was, they were supposed to get permission to test someone, and in some cases were denied permission to test patients they thought might have COVID, b/c the person how no risk factor, which were only two of…out of the country in China, or close contact with someone known to be infected.
Those criterion are guaranteed to miss cases when it is spreading at first.

John Tillman
Reply to  John Tillman
October 17, 2020 6:49 pm

Bessides problems like those was the fact of asymptomatic cases, the extent of which wasn’t known, which led to estimates of fatality rates ten times too high.

The fact is however that even most very old people recover, and more so now that medical professionals know better how to treat patients, so that treatment-caused fatalities have declined.

Some epidemiologists think that the 1889 Russian flu was caused by coronavirus OC43, which is now a common cold agent, one of seven known human CoVs and, like SARS-1, MERS and SARS-2, a betacoronavirus, as is another of the cold CoVs. The other two are alphaCoVs. The majority of adult colds are caused by those four CoVs.

https://en.wikipedia.org/wiki/1889%E2%80%931890_pandemic

Others think it was flu, which conferred immunity against Spanish flu among people old enough to have been exposed to it.

John Tillman
Reply to  Keith Sketchley
October 17, 2020 5:12 pm

This great 2018 paper on RNA virus phylogeny shows that the NIH isn’t totally useless:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282212/

Origins and Evolution of the Global RNA Virome

Reply to  Keith Sketchley
October 17, 2020 5:39 pm

Wuhan is a huge industrial city with many direct international flights in and out every day.
And the virus was almost surely spreading for weeks before anyone knew anything about it, and when the initial implications grew more clear, the flights continued for some time after that.
One thing we do know, it was spreading widely over there and in Italy and here in the for long enough that is was all over the place by the time the number of known cases and then deaths suddenly jumped up through the roof.
The CDC was still saying no one had anything to worry about and there was no evidence of community transmission while it was known to have spread widely in Washington State, and no one had any idea how first that teen aged kid and then that nursing home had acquired the infection…which was far away from the guy who was know to have arrived from China with it and was in the hospital.
And while they issued glib assurances that there was no evidence of community transmission, they had no testing capacity and no surveillance and were not actually looking for it or even coming up with a plan for what to do if the situation changed…which it had already done while they were snoozing.

John Tillman
Reply to  Nicholas McGinley
October 17, 2020 5:48 pm

CDC actions and inactions have been terrible, to include faulty test kits after Obama made them the only source for viral tests.

However, had the CPC lived up to its WHO obligations, informed the world as soon as the outbreak was recognized and let in foreign specialists, US and other authorities would have known more. Instead the ChiCom regime covered up, delayed, arrested honest, brave whistleblowers and let international flights continue unabated.

Mass murder, economic warfare and election interference by the criminal CPC vs. bureaucratic incompetence by the CDC. FauXi and other Western co-conspirators are however accomplices both before and after the fact.

whiten
Reply to  Nicholas McGinley
October 17, 2020 6:54 pm

Nicholas McGinley
October 17, 2020 at 5:39 pm

A convincing fiction story, not even a science fiction one.
But wholly non realistic.

cheers

Reply to  whiten
October 19, 2020 2:43 am

Everything I said in that comment is a documented fact.
What exactly do you think is fiction?
Not that I really care.
But I am curious if you can actually explain what you say.
Saying “No, wrong” is not even a worthy drive by effort at trolling.
On second thought, do not bother to respond.
You have never said one single sentence that has any value whatsoever, in all the years you have been bothering everyone here.
I doubt you would break that streak here and now.

Reply to  Nicholas McGinley
October 19, 2020 4:57 am

Whiten,
I took you to mean my comment is a fiction.
But perhaps you meant the headline post is one.
If so I owe you an apology.

whiten
Reply to  Nicholas McGinley
October 19, 2020 8:21 am

Nicholas McGinley
October 19, 2020 at 4:57 am

Sorry, but;
Yes I meant your comment is fiction.
You do not know even the very basics of virology.

No new virus, especially “airborne” one, can go global Pandemic in maters of weeks or few months.
Needs replication through production and reproduction.
Needs the “grounds” to do that.
Needs to dominate over other viruses that utilizing the same grounds.
That takes more than three full cycles, technically ~2 years at the very least to get the critical “mass” for a full seasonal global blow, if it could at all, in consideration of a global Pandemic.

So whatever your facts are, in consideration of how global Pandemics could be, these facts give you a fictional vision.

You are welcome to stick by it and believe it.
But it wont hurt if you give it a second thought… just in case.

cheers

Reply to  Nicholas McGinley
October 19, 2020 2:15 pm

I suppose you have not been keeping up with current events.
It did happen.
And I can promise you that not only have I forgotten more virology than you will ever learn, I alone among the two of us am grounded in reality.
Your inane babbling is not even interesting from a mental health oddities perspective.

October 17, 2020 6:50 pm

“From down in the comments it is noted that “hydroxychloroquine did show excellent results just for prophylaxis of diabetes” in a paper from April, 2019. So it seems that diabetic drugs are effective against the Wuhan virus, perhaps all of them.“

Is illogical, backwards. You can’t properly say that since a medicine effective in some cases of COVID-19 _when used with other substances_ is effectice with diabetes the reverse path is true.

Medicines to combat diabetes very widely in the way they function, note the study customers were taking a two-medicine combination. So I take ‘perhaps all of them’ as ignorant speculation. (That’s just like climate alarmism.)

Metformin is of course well known, used in Europe for decades before the US got off its duff and accepted it, Canada in between in time. It is a very good medicine for diabetes because it has low risk of hypglycemia which is immediately life threatening whereas hyperglycemis is not. Earlier medicines had risk.

Insulin has risk of hypoglycemia, it is fundamentally different from other medicines for diabetes.

In the study, the anti-malaria medicine reduced swelling, which is considered good against COVID-19. It is also less costly, Metformin by itself is not costly but customers in the study were taking a combination.

And where did ‘hit job on Metformin’ come from? I didn’t see anything covering that in this article. There is a tone of conspiracy theory, to which Occam’s Razor should be applied.

(BTW, results of using anti-malaria drugs to treat COVID-19 have varied, perhaps sloppy research, perhaps timing of application, perhaps that they may only be effective in combination with other medicines. Much sloppiness and flapping about in this panicdemic.)

Anthony! Are you sleeping?

Reply to  Keith Sketchley
October 18, 2020 3:38 am

Maybe Ayn Rand’s Atlas shrugged?

c1ue
October 17, 2020 9:19 pm

I kept looking for the /sarc or /darksatire but it was not to be found.

October 18, 2020 3:11 am

British establishment has become unhinged – my bold :
Ken McCallum, the newly appointed Director General of the U.K.’s MI5 (née Military Intelligence, Section 5), declared China to be the U.K.’s primary adversary this past Wednesday, Oct. 14, in his first public appearance. He said that MI5 is “looking to do more against Chinese activity, carefully prioritized…. You might think in terms of the Russian intelligence services providing bursts of bad weather, while China is changing the climate,” he said.

This sure beats David Archibald for feverish frothing, but is at least funny.
So there we have it, the difference between Russia and China is weather and Climate, get it?

davidgmillsatty
October 18, 2020 4:52 pm

Where is the published peer reviewed paper that says Covid 19 was man made and not natural. Time and time again I have looked and so far nothing. You would think that with all of the hatred in the world it would not be hard for some scientist somewhere to publish a peer reviewed paper in a reputable journal or even in an open journal proving that Covid 19 was man made. Have yet to see it. Have read many that say that have concluded it is natural.

I want to see the paper that proves your thesis.

John Tillman
Reply to  davidgmillsatty
October 18, 2020 8:01 pm

Peer review is pal review is political review.

Please just look at the papers linked here showing gain of function research on SARS-related coronaviruses. It’s an open and shut case.

davidgmillsatty
Reply to  John Tillman
October 19, 2020 8:29 am

Nonsense. Just showing that there is gain of function research on coronaviruses does not mean that gain of function was the cause. Correlation is not causation is a quote often used on this site and it applies here as well.

Here is a finding from a recent paper:

“The researchers found that the lineage of viruses to which SARS-CoV-2 belongs diverged from other bat viruses about 40-70 years ago. Importantly, although SARS-CoV-2 is genetically similar (about 96%) to the RaTG13 coronavirus, which was sampled from a Rhinolophus affinis horseshoe bat in 2013 in Yunnan province, China, the team found that it diverged from RaTG13 a relatively long time ago, in 1969.”

https://www.sciencedaily.com/releases/2020/07/200728113512.htm

Where is the gain of function on this particular lineage that was not even known till last July?

Reply to  davidgmillsatty
October 19, 2020 12:41 pm

There’s a theory that some miners caught a then unknown virus and were in hospital for a few years.

There’s also a claim that since bats are relatively unaffected by SARS type virus it tends to evolve more quickly in them.

Yes, many theories….

John Tillman
Reply to  Keith Sketchley
October 19, 2020 1:38 pm

The fact is that Shi and colleagues were actively evolving a SARS-like CoV to be able to break into human lung cells more easily. They did this at UNC until funding for this dangerous, potentially lethal “research” was temporarily halted in the US. Then Shi went hom to China to continue the same line of “work” in the new BSL-4 lab at the WIV. FauXi provided new financing when the moratorium was lifted.

John Tillman
Reply to  John Tillman
October 19, 2020 9:39 am

There was GoF “work” at UNC and WIV on not just any CoV, but a SARS-like strain from the same caves as SARS. Bat Woman and her colleagues were specifically evolving SARS-related CoVs to improve their ability to infect lung cells through the very receptor used by the COVID-19 pathogen. It’s nonsensical to buy into any of the lame stories floated by the CCP.

The novel CoV did not evolve in bats and pangolins, as the Communists lied.

It’s the same lineage as SARS. When that lineage diverged from related CoVs isn’t relevant.

The novel CoV didn’t come from the wild. It comes from a population of bats in Yunnan, so no farmer in Hubei harvesting guano in bat caves could have picked it up either. It was evolved at the WIV, from which it either escaped accidentally or was intentionally released.

davidgmillsatty
Reply to  John Tillman
October 19, 2020 10:52 am

Nothing but opinion and that is all you have. You obviously don’t like or understand virology research and seem to have the opinion that scientists who have the opportunity to do evil will do it.

There are now at least six known non-recombinant strains of Covid (last I checked). Your thesis would require any scientist who would do this to be able to predict how many strains would evolve and whether any would evolve by recombination and become even far more deadly than anyone could possibly know, and how they would effect individuals differently.

The idea that scientists would do this is a bit like saying the military would launch a nuclear warhead with no control over it.

John Tillman
Reply to  davidgmillsatty
October 19, 2020 1:29 pm

I do like and understand real virus research. But I’m hardly alone in opposing GoF using ferrets to mimic human lung tissue in order to find new ways of infecting cells.

I have linked to some of the many highly respected virologists who objected to GoF “research” as dangerous. The Obama Administration briefly heeded their warnings about the threat, but then resumed funding this risky “work”. It’s not only risky, but has not produced any useful results.

Saying that GoF development of novel viral strains is dangerous is simply a fact. Clearly, labs have frequently lost control of lethal pathogens.

davidgmillsatty
Reply to  John Tillman
October 19, 2020 12:33 pm

My how the GOF story has morphed. First the virus originated right outside the Wuhan lab. Then it originated just a few blocks away, then it was 8 miles away and a thirty minute bus ride and now the virus originated in Yunnan 2000 miles away. So now the story has to be a bat was taken from the lab to Yunnan 2000 miles away where it was released and then the virus got back to Wuhan and infected someone there. Somehow the virus got to Wuhan, 2000 miles away without infecting anyone in between.

The GOF story gets more preposterous every day.

John Tillman
Reply to  davidgmillsatty
October 19, 2020 1:33 pm

The facts haven’t morphed. It was always known that the SARS-like CoVs came from Yunnan. Bat Woman Shi’s virus hunting in the caves there was populatized.

Many papers published while she was at UNC and WIV all made plain that the GoF procedures were conducted on SARS-related viruses found in the Yunnan caves, whence came SARS.

davidgmillsatty
Reply to  davidgmillsatty
October 19, 2020 4:59 pm

You are only missing about a dozen steps between the study of these viruses and gain of function (could be loss as well) being the cause of Covid.

Steven Mosher
October 18, 2020 8:19 pm

as for Davids lie about the funding

The 3.7 Million was Not directly to Wuhan, it went to ecohealth

In 2014, the NIH approved a grant to ecohealth alliance designated for research into “Understanding the Risk of Bat Coronavirus Emergence.” This involved collaborating with researchers at the Wuhan Institute to study coronaviruses in bats and the risk of potential transfer to humans. Other agencies and researchers NOT IN WUHAN also recieved
portions of this 3.7M

The project wanted to understand what factors allow coronaviruses, including close relatives to SARS, to evolve and transfer into the human population

Over the entire history the Wuhan Institute received about $600,000 from the NIH. the money was a fee for gathering and analysing of bat samples.

the research was not for gain of function
https://projectreporter.nih.gov/project_info_description.cfm?aid=9819304&icde=49588715
” Aim 1. Characterize the diversity and distribution of high spillover-risk SARSr-CoVs in bats in southern China. We will use phylogeographic and viral discovery curve analyses to target additional bat sample collection and molecular CoV screening to fill in gaps in our previous sampling and fully characterize natural SARSr-CoV diversity in southern China. We will sequence receptor binding domains (spike proteins) to identify viruses with the highest potential for spillover which we will include in our experimental investigations (Aim 3). Aim 2. Community, and clinic-based syndromic, surveillance to capture SARSr-CoV spillover, routes of exposure and potential public health consequences. We will conduct biological-behavioral surveillance in high-risk populations, with known bat contact, in community and clinical settings to 1) identify risk factors for serological and PCR evidence of bat SARSr-CoVs; & 2) assess possible health effects of SARSr-CoVs infection in people. We will analyze bat-CoV serology against human-wildlife contact and exposure data to quantify risk factors and health impacts of SARSr-CoV spillover. Aim 3. In vitro and in vivo characterization of SARSr-CoV spillover risk, coupled with spatial and phylogenetic analyses to identify the regions and viruses of public health concern. We will use S protein sequence data, infectious clone technology, in vitro and in vivo infection experiments and analysis of receptor binding to test the hypothesis that % divergence thresholds in S protein sequences predict spillover potential. We will combine these data with bat host distribution, viral diversity and phylogeny, human survey of risk behaviors and illness, and serology to identify SARSr-CoV spillover risk hotspots across southern China. Together these data and analyses will be critical for the future development of public health interventions and enhanced surveillance to prevent the re-emergence of SARS or the emergence of a novel SARSr-CoV.”

~$133,000 was sent to wuhan in the first four years ~ $66,000 coming in the last year. For In 2019 ~$76,000 was budgeted but no money was actually sent.

Here is the top level link,

https://taggs.hhs.gov/Detail/AwardDetail?arg_AwardNum=R01AI110964&arg_ProgOfficeCode=104

if you contact ecohealth, they can verify the small sums that went to wuhan and verify the ~600K figure

David Archibald
Reply to  Steven Mosher
October 19, 2020 6:08 am

But, but the US consulate in Wuhan had visiting rights to the Institute of Virology and so wrote reports saying how slack biosecurity standards were there. If it is no big deal, how come that happened? Any funding of Wuhan was guaranteed to produce a pandemic. Fauci knew that. Fauci was getting bang for the buck for his misanthropic delusions. Global warming is the religion of choice for militant atheists, without which their meaningless lives would be shallow, hollow, depressing and purposeless.

c1ue
Reply to  David Archibald
October 19, 2020 8:49 am

David,
All you write can be true, but the big step is still that SARS-2-COV is a novel new infection path – one which the leading virologists/geneticists in the world in that area were unaware of.
In order to create SARS-2-COV – this path would have to be discovered (possible but less likely), it would have to be tested (no evidence of testing), and then it would have to be leaked or released (no evidence of this at all).
It is really hard finding/making new things – even with CRISPR.
I would suggest looking at the work being done by this startup trying to create pig organs that can be transplanted into people: https://www.technologyreview.com/2019/06/12/239014/crispr-pig-organs-are-being-implanted-in-monkeys-to-see-if-theyre-safe-for-humans/
Here – they know what they are aiming for, they can test this openly and they have the CRISPR tech and all its associated support companies/knowledge/infrastructure.
I’m not saying it is impossible that SARS-2-COV is man-made, but I am saying that the presence of a Wuhan lab isn’t meaningful itself (a lot of cities have virus research labs including LA, NY, SF etc).

John Tillman
Reply to  c1ue
October 19, 2020 10:01 am

The GoF “researchers” at the WIV were indeed evolving a SARS-like CoV from Yunnan bat caves better to infect human lung cells, using ferrets as models. Before such insanely risky procedures were temporarily shut down in the US, Shi “Bat Woman” Zheng-Li and colleagues were doing the same thing at UNC.

It’s not just that the lab is in Wuhan, but what Shi and her colleagues were doing there. Do you really believe their “work” at the BSL-4 lab to be merely coincidental?

Reply to  John Tillman
October 20, 2020 5:17 am

This guy seems to think that the market was not actually where the outbreak originated, but so far I have not located anything more from him on this.
Kind of an annoying place to end an article:
“And while many believe the virus originated at a fish market in Wuhan, China, Garry said that is also a misconception.

“Our analyses, and others too, point to an earlier origin than that,” Garry said. “There were definitely cases there, but that wasn’t the origin of the virus.”

https://abcnews.go.com/US/conspiracy-theorists-study-concludes-covid-19-laboratory-construct/story?id=69827832

Reply to  John Tillman
October 20, 2020 5:48 am

It makes sense that the virus was around for some time before it was picked up on by doctors and health authorities.
It sure did a lot of spreading in other countries before anyone was aware of how extensively it was spreading, and indeed that it was spreading at all. And that was after everyone knew there was a new virus and were presumably at least somewhat alert for it.

“The high school boy in Snohomish County became ill with flu-like symptoms last Monday, the student’s family said in a statement.

He was tested for the flu but the tests came back negative, so he returned to Jackson High School on Friday, the county health district said in a blog post.

He stayed on campus about five minutes and went home because the family was notified by health officials that his original sample had been tested for coronavirus and came back presumptive positive, the health district said.

“The family didn’t know their son was being tested for COVID-19…. Like most people, they assumed it was the flu. They did all the right things,” the health district said.

The high school was closed over the weekend and will be closed Monday to allow for a thorough cleaning and disinfecting before the students return.

District health officials say they are investigating this case since it suggests that local transmission of COVID-19 is occurring.”

No one had any idea how a high school kid in a different county had got infected.
And no one knew how it got to that nursing home either.
I think this virus can spread for weeks if not months among young people, almost none of whom get sick enough to wind up in a hospital, and that it becomes known to health authorities only when it spreads into a population of elderly individuals and then starts to make people sick enough to wind up in a hospital.
It is the low level of virulence in a large number of people who get it, coupled with long latency, rapid spread, and long period before the second phase of the illness manifests, that allow it to spread widely and quickly and silently.
Knowing all of this and looking back at when the first cases became known, it seems unlikely that it was noticed soon after it passed into people and began to spread.
Impossible even.

(Of course all of this is leaving aside for the purpose of discussion the possibility it was deliberately or accidental released from that lab.)

https://www.sciencemag.org/news/2020/01/wuhan-seafood-market-may-not-be-source-novel-virus-spreading-globally

c1ue
Reply to  John Tillman
October 20, 2020 7:52 am

1) Correlation is not causation
2) I outlined multiple areas where specific evidence could provide more proof – I have seen none of that.
3) Most of the recent animal to human virus crossings in the past 2 decades were in China. These include: H1N1, SARS1, swine flu etc
Why exactly would not China be researching animal viruses?
4) As I noted before – most large cities in the US host virus research as well. New York, San Francisco, LA and Chicago among them.
If all you can brandish is coincidence, it is a very weak argument.

Reply to  c1ue
October 20, 2020 5:13 am

We pass around research papers in which drugs are tested for antiviral activity against SARS and MERS and COVID.
Where does anyone think these studies are being done?
We have viral genome family trees for entire complex webs of virus families, that includes info on what strains of which viruses can be found in certain animals in certain places.
How does anyone suppose all of this info is gleaned…and more to the point, where?
There are guidelines about what sort of bio containment you need to work with various infectious disease organisms.
For the worst deadly stuff, it is BSL-4.
For SARS and COVID, it is BSL-3
It behooved us to make sure that people in other places have safe facilities to work with this stuff.
Because we can all now get an idea of what can happen.

Steven Mosher
Reply to  David Archibald
October 19, 2020 11:48 pm

“But, but the US consulate in Wuhan had visiting rights to the Institute of Virology and so wrote reports saying how slack biosecurity standards were there. If it is no big deal, how come that happened? Any funding of Wuhan was guaranteed to produce a pandemic. Fauci knew that. Fauci was getting bang for the buck for his misanthropic delusions. Global warming is the religion of choice for militant atheists, without which their meaningless lives would be shallow, hollow, depressing and purposeless.”

there is NO evidence that Wuhan institute received 3.7M for gain of function
The evidence is that they received on the order of 600K for collecting samples.

there is no evidence that any gain of function was carried on under the contract
IF you have evidence that there was then you can collect a reward by filing a fraud claim
as the SOW for the contract did not authorize gain of function activities.

IF you have evidence file a claim, the reward is 3X the value of the contract.

1. You have no evidence
2. the evidence that exists indicates MUCH LESS than 3.7M directed to wuhan
3. the evidence that exists indicates this was for collection of samples.

The real question is this. IF you have evidence then what is your motivation in
refusing to file a fraud claim?

david are you being paid by the enemies of china to raise false issues?

until you can prove that you are not a paid state agent I think we have evidence that you are.
Perhaps the Russians are paying you again, like they probably did for your grippen work

what else could explain your refusal to take the evidence you have and file a fraud charge.

Reply to  Steven Mosher
October 20, 2020 6:20 am

Is that lab in Wuhan also the site of the local hospital?
Because if so, it may have been first noticed there because that is where there were people who would recognize a new virus when it appeared in patients.
The market was a site of commerce on a large scale, and presumably had people coming and going from other regions making deliveries of food and animals.
If an infected person passed it to a bunch of people in that market, and then left, it would seem that the virus popped up around and in that market.
Other studies from past years have documented that in the parts of Guangdong that has bats with closely related viruses, nearby villagers have about a 6% chance of having antibodies to those corona viruses. So people in such a village could be immune or mostly immune by dint of having had it circulating around for some period of time.

Dr. Gene Bert Walker
October 19, 2020 5:03 am

One of the false arguments made in the legacy media outlets is that humans cannot create such lethal viruses by genetic manipulation
In your abbreviated history of the origin of Sars CoV-2 virus, the virus that causes Covid 19 you left out what is perhaps one of the most pivotal studies involving viral genetic manipulation which actually though inadvertently produced a highly infectious and virulent virus.
The study is “Jackson RJ, Ramsay AJ, Christensen CD, Beaton S, Hall DF, Ramshaw IA (2001) Expression of mouse interleukin-4 by a recombinant ectromelia virus suppresses cytolytic lymphocyte responses and overcomes genetic resistance to mousepox. J Virol 75: 1205–1210”
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC114026/
read a review of the studies implications here:
“The mousepox experience”
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2816623/
It involved researchers who inserted a gene for Interlukin 4 into a mouse pox virus. the resultant virus was lethal to both immunized and native mice, including all the mice which were not in the actual study but were present in the lab.

Reply to  Dr. Gene Bert Walker
October 19, 2020 7:52 am

I am not sure anyone here has said it could not be done, or that it is impossible to create a lethal virus.
Just that the scenario offered here seems more like speculation that evidence.

Every time a house burns down it COULD have been arson, until someone finds out one way or the other how it actually did start.
And even for something like a house fire, investigators have been found to be notably and heinously wrong.

John Tillman
Reply to  Nicholas McGinley
October 19, 2020 9:44 am

No speculation required. By GoF in ferrets, the WIV was evolving SARS-like CoVs from Yunnan bats in order for them better to attack the very receptor used by the COVID-19 agent.

That’s more like an open and shut case. Accused have been convicted on far less circumstantial evidence than that. Why do you suppose that the regime wouldn’t let foreign specialists investigate in Wuhan?

Reply to  John Tillman
October 20, 2020 7:01 am

I can think of other reasons than to cover up where the virus came from or how it came to exist.
Like for example they were wanting to keep the extent of the outbreak from being reported.
My recollection is they did many things in the initial stages that made it must worse for them, like not cancelling some key events that led to many people travelling around.
I am not clear on if the supposition you are going on is that the release was an accident or deliberate…aside from the origin.
It is a little hard to understand why they would release a deliberately created bioweapon virus on themselves.

Reply to  John Tillman
October 20, 2020 7:36 am

” Accused have been convicted on far less circumstantial evidence than that.”
Less evidence than “They were doing research on similar viruses, therefore they created it deliberately?”

There is a large volume of material published from many researchers all over the world in which they conclude that all the evidence points away from it being manufactured.
Having suspicions and a scenario is not a refutation of any of that.
Evidence has to be specific to this viral genome.
The only part of the virus that has not been found in wild virus samples seems to be the spike.
But viruses evolve the ability to jump into people all the time, including all of the known human corona viruses, two in the past 20 years prior to this.

In any case, I think it is more productive to look this from a scientific point of view, not from a prosecutorial one.

Personally, I want to know facts and hear evidence about how this happened, and jumping to conclusions preempts fact finding.

Reply to  Dr. Gene Bert Walker
October 19, 2020 7:54 am

The media is a different story.
No accounting for what those idiots say.
They want to blame every death on the one world leader who took a decisive early step to block the spread, and who no one thinks has any particular medical or public health knowledge.

c1ue
Reply to  Dr. Gene Bert Walker
October 20, 2020 7:57 am

The example in question was able to test vs. mice.
Where was the human testing in Wuhan?
Real world biological research has shown it is very difficult to achieve anything in biology, even using CRISPR and similar “targeted” tools.
It took 4 years, for example, to create a treatment for a single codon fix for sickle cell.
Alleging SARS-2-COV is man-made requires also showing how it was discovered (the infection pathway was unknown to science until COVID-19 appeared) and how it was tested (mice breed and die quickly, cheaply and anonymously. Humans, not so much).
There’s also the question of how it spread. If the Wuhan lab was truly creating bio-weapons – that’s a completely different level of risk than doing preventative research.
I could much more believe an accidental release from a non-bioweapon research effort – but even evidence for that is non-existent.

LOL@Klimate Katastrophe Kooks
October 21, 2020 4:50 pm

Rahman et al. (2020) [1] demonstrated by in silico studies that iridoids, diterpenes and lignans are promising anti-SARS-CoV-2 treatments through TMPRSS2 interaction.

Certain species of trees emit diterpenes… it’d be interesting to cross-correlate areas where people got CoV19, were treated with HCQ with good results, and the preponderance of diterpene-emitting flora in the area (or the average diterpene atmospheric concentration in the area).

That may at least partly explain why HCQ seems to work for some, and not for others. The HCQ inhibits ACE2 enzyme expression, reducing sialic acid biosynthesis, thus blocking CoV19 from attaching to cells via that route, but it can use an alternate route, that of the TMPRSS2 enzyme.

In order to completely block CoV19 from attaching to and infecting cells, one must use an ACE2 inhibitor (quinine, chloroquine, hydroxychloroquine, etc.), and a TMPRSS2 inhibitor (camostat mesylate, diterpene, etc.)

So if the hypothesis holds, people in areas with large stands of evergreen trees (for example) would find treatment with HCQ alone to be effective, whereas people in cities or areas with no evergreen trees would require treatment with HCQ and a TMPRSS2 inhibitor in order to be effective.

Does anyone here have the data and ability to do such a cross-correlation?

[1] N. Rahman , Z. Basharat , M. Yousuf , G. Castaldo , L. Rastrelli and H. Khan , Molecules, 2020, 25 , 2271

Philip Mulholland
Reply to  LOL@Klimate Katastrophe Kooks
October 21, 2020 5:26 pm

Diterpene
Hmm
Abietane is a diterpene
Hmm
Abietic acid is found in pine wood.
Hmm
Are pine nuts any good?

LOL@Klimate Katastrophe Kooks
Reply to  Philip Mulholland
October 21, 2020 7:29 pm
LOL@Klimate Katastrophe Kooks
Reply to  LOL@Klimate Katastrophe Kooks
October 21, 2020 7:09 pm

Ok, I did some quick checking… but I’m no statistician, so I don’t really know what to make of the data below. I used counties in the Blue Ridge Mountain range… those mountains are ‘blue’ because of the terpines the trees emit. I’m sure there are a lot of factors to control for, but as I said, I’m not a statistician. Perhaps someone can do something with this.

I only did GA, but there are also counties in PA, MA, WV, VA, NC, SC, TN which are in the Blue Ridge Mountain range.

The list is sorted (descending) by percentage of deaths vs. total county population.

Habersham County, GA
Total population: 45328
CoV19 deaths: 75
%: 0.16546064242852100247087892693258

Stephens County, GA
Total population: 25925
CoV19 deaths: 41
%: 0.15814850530376084860173577627772

Chatooga County, GA
Total population: 24789
CoV19 deaths: 27
%: 0.10891927871233208277865182137238

Fannin County, GA
Total population: 26188
CoV19 deaths: 28
%: 0.10691919963341988697113181609898

Union County, GA
Total population: 24511
CoV19 deaths: 25
%: 0.1019950226428950267226959324385

Towns County, GA
Total population: 12037
CoV19 deaths: 12
%: 0.09969261443881365788817811747113

Bartow County, GA
Total population: 107738
CoV19 deaths: 93
%: 0.08632051829438081271232062967569

Hall County, GA
Total population: 204441
CoV19 deaths: 168
%: 0.08217529751859949814371872569592

White County, GA
Total population: 30798
CoV19 deaths: 23
%: 0.07468017403727514773686603026171

Franklin County, GA
Total population: 23349
CoV19 deaths: 17
%: 0.07280825731294702128570816737334

—————————————-
Above: 525104 population | 509 deaths | 0.09693317895121728267162314512935% avg.
—————————————-
US
Total population: 330480852
CoV19 deaths: 227347
%: 0.06879279045189583328718845108763
—————————————-
Below: 1648313 population | 714 deaths | 0.04331701563962669711395833194302% avg.
—————————————-

Rabun County, GA
Total population: 17137
CoV19 deaths: 11
%: 0.06418859777090505922856976133512

Carroll County, GA
Total population: 119992
CoV19 deaths: 75
%: 0.06250416694446296419761317421161

Walker County, GA
Total population: 69761
CoV19 deaths: 43
%: 0.06163902466994452487779704992761

Hart County, GA
Total population: 26205
CoV19 deaths: 16
%: 0.06105705018126311772562488074795

Gilmer County, GA
Total population: 31369
CoV19 deaths: 19
%: 0.06056935190793458509993943064809

Whitfield County, GA
Total population: 104628
CoV19 deaths: 63
%: 0.06021332721642390182360362426884

Barrow County, GA
Total population: 83240
CoV19 deaths: 50
%: 0.06006727534839019702066314271985

Polk County, GA
Total population: 42613
CoV19 deaths: 25
%: 0.05866754276863867833759650810785

Floyd County, GA
Total population: 94498
CoV19 deaths: 55
%: 0.05820228999555546149124849203158

Jackson County, GA
Total population: 72977
CoV19 deaths: 40
%: 0.05481179001603244857968949120956

Elbert County, GA
Total population: 19194
CoV19 deaths: 9
%: 0.04688965301656767739918724601438

Banks County, GA
Total population: 19234
CoV19 deaths: 8
%: 0.04679213892066132889674534678174

Lumpkin County, GA
Total population: 33610
CoV19 deaths: 14
%: 0.04165426956263016959238321927998

Cherokee County, GA
Total population: 258773
CoV19 deaths: 100
%: 0.03864390798112631534201790758696

Dawson County, GA
Total population: 26108
CoV19 deaths: 10
%: 0.03830243603493182166385782135744

Madison County, GA
Total population: 29880
CoV19 deaths: 11
%: 0.03681392235609103078982597054886

Paulding County, GA
Total population: 168667
CoV19 deaths: 60
%: 0.03557305222716951152270450058399

Haralson County, GA
Total population: 29792
CoV19 deaths: 10
%: 0.03356605800214822771213748657358

Dade County, GA
Total population: 16116
CoV19 deaths: 5
%: 0.03102506825515016133035492678084

Pickens County, GA
Total population: 32591
CoV19 deaths: 10
%: 0.0306833174802859685189162652266

Catoosa County, GA
Total population: 67580
CoV19 deaths: 20
%: 0.02959455460195324060372891387985

Forsyth County, GA
Total population: 244252
CoV19 deaths: 52
%: 0.02128948790593321651409200334081

Murray County, GA
Total population: 40096
CoV19 deaths: 8
%: 0.01995211492418196328810853950519